1-[bis[3-(dimethylamino)propyl]amino]propan-2-ol

Flammability

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

pyrophoric liquids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

02-05-2012

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.13 (Pyrophoric Properties of Solids and Liquids)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch number of test material: PFW100207
- Purity: contains 0.03% water
- Physical state: Liquid

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: in cool, well-ventilated area

Key result

Test procedure:

ignition time on contact with air

Remarks:

Ignition on contact with air refers to either Pyrophoric solids or Pyrophoric liquids depending on physical state.

Remarks on result:

no ignition on contact with air (not further specified)

As the first test was negative, the second test was also performed.

No ignition or charring was observed during any test. The sample is therefore not a pyrophoric liquid.

Interpretation of results:

GHS criteria not met

Conclusions:

No ignition or charring was observed during any test. The sample is therefore not a pyrophoric liquid.

Reference 2

Endpoint:

flammable solids

Data waiving:

study technically not feasible

Justification for data waiving:

the study does not need to be conducted because the substance is a liquid

Reference 3

Endpoint:

substances / mixtures which in contact with water emit flammable gases

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2012-05-02 to 2012-05-04

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.12 (Flammability (Contact with Water))

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch number of test material: PFW100207
- Purity: contains 0.03% water
- Physical state: Liquid

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: in cool, well-ventilated area

Remarks on result:

no reaction with water observed

Test results - Initial Tests:

No gas generation or spontaneous ignitions were observed during any of the tests.

Test results - Final Test:

No gas generation or spontaneous ignitions were observed during any of the tests. The sample does not generate flammable gases in contact with water.

Interpretation of results:

GHS criteria not met

Conclusions:

No gas generation or spontaneous ingitions were observed during any of the tests. The sample does not generate flammable gases in contact with water.

Description of key information

The test substance is concluded not to be pyrophoric, nor flammable in contact with water following GLP-compliant studies in accordance with EC test methods A.12 and A.13 (Younis S, 2012). In addition, the test substance does not need to be classified as flammable liquid as the flash-point was determined to be 132°C and is therefore outside the range relevant for classification according to the CLP regulation.

Key value for chemical safety assessment

Flammability:

not classified

Justification for classification or non-classification

The test substance does not need to be classified as flammable liquid as the flash-point was determined to be 132°C and is therefore outside the range relevant for classification and labelling under the CLP Regulation. Furthermore, the test substance is tested not to have pyrophoric properties nor to be flammable in contact with water.