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EC number: 812-925-4 | CAS number: 1639345-42-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- August 25 - November 16, 2016
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 016
- Report date:
- 2016
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Version / remarks:
- Adopted 17 th July, 1992
- Deviations:
- no
- GLP compliance:
- no
- Remarks:
- The study was perfonned according to the study plan and SOPs, which was in compliance with the "Guidelines of Chemical Testing Good Laboratory Practices" (Ministry of Environmental Protection of the People's Republic of China).
Test material
- Reference substance name:
- 4-[fluoro(dimethyl)silyl]butanenitrile
- EC Number:
- 812-925-4
- Cas Number:
- 1639345-42-8
- Molecular formula:
- C6H12FNSi
- IUPAC Name:
- 4-[fluoro(dimethyl)silyl]butanenitrile
- Test material form:
- liquid
- Details on test material:
- - Purity test date: 97.7% Silane, 3-cyanopropyl dimethyl fluoro; 1-1.4% Silane, 2-cyanopropyl dimethyl fluoro
- Lot/batch No.: SO408
- Expiration date of the lot/batch: November 2016
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): Aeration tank of Liede Sewage Treatment Plant of Guangzhou
- Treatment: The sludge was removed any coarse particles and impurities on the surface, then was washed with the test medium (1 lOOg, lOmin, repeated for 3 times), the supernatant liquid phase was decanted and the solids was re-suspended in the test medium. The sludge suspension was detennined as 8.3g/L. Kept it aeration until required. When testing, the inoculum was diluted to 4.0g/L and added to each test vessel to give a final concentration of 30mg suspended solids per liter.
- Determination of cell number: The total number of cell in the test system was detennined as 4.0x10E7 cfu/L. - Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 75 mg/L
- Based on:
- act. ingr.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
All of the test bottles were stirred and incubated on OxiTop® Control BOD Test System at 22°C± 1°C in the dark and closed condition over 28 days.
CONTROL AND BLANK SYSTEM
Bottles 1, 2 & A (test suspension) Containing test substance, inoculum and test medium
Bottles 3, 4& B (inoculum blank) Containing inoculum and test medium
Bottle 5 (procedure control) Containing reference substance, inoculum and test medium
Bottle 6 (toxicity control) Containing test substance, reference substance, inoculum and test medium
Note: Bottles A & 8 for determination of nitrite and nitrate concentrations at the start of the test.
Reference substance
- Reference substance:
- benzoic acid, sodium salt
Results and discussion
% Degradation
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 43.9
- Sampling time:
- 28 d
- Remarks on result:
- other: mean of two replicates
- Details on results:
- Determination of the nitrite and nitrate concentrations of bottles A and B at the start of the test: As the results showed that the test substance cannot be considered to be readily biodegradable, the nitrite and nitrate concentrations of bottles 1, 2, 3, 4 were not determined at the end of the test.
BOD5 / COD results
- Results with reference substance:
- 97.7% after 14 d. Thus, the 60% pass level was reached.
Any other information on results incl. tables
The toxicity control attained 50.5% degradation after 14 d. Thus, the test substance is not inhibitory to the inoculum.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- The percentage biodegradation of the test substance was 43.9% at the end of the test under the conditions of the study, so the test substance cannot be considered to be readily biodegradable.
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