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EC number: 800-309-8 | CAS number: 231297-75-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Acute toxicity to freshwater fish:
No toxicity observed even at highest concentration level tested.
RA_CAS71786-47-5_OECD 203_Pimephales promelas: LL50 (96h) > 1000 mg/L WAF
RA_CAS115733-09-0_OECD 203_Oncorhynchus mykiss: LL50(96h) > 100 mg/L WAF
Acute toxicity to saltwater fish:
No toxicity observed even at highest concentration level tested.
RA_CAS71786-47-5_OECD 203_Cyprinodon variegatus: LL50 (96h) > 10000 mg/L WAF
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 1 000 mg/L
Marine water fish
Marine water fish
- Effect concentration:
- 10 000 mg/L
Additional information
General considerations
The acute toxicity to fish was investigated for different analogues structures of the magnesium sulfonate target substance (CAS 231297-75-9). For the substance itself, no experimental data are available. Since all substances used belong to the same chemical group, aryl-alkyl sulfonates, the same behaviour and toxicity potential can be expected. The following read-across substances were used to fulfil the endpoint of short-term toxicity to freshwater fish: Magnesium sulfonate read-across substance (CAS 71786-47-5) and calcium sulfonate read-across substance (CAS 115733-09-0). Investigations concerning toxicity in marine fish were performed with the magnesium sulfonate read-across substance (CAS 71786-47-5). For the detailed procedure of the read-across principle and justifications, please refer to the Read-Across Statement (attached to this document).
Acute toxicity to freshwater fish
All available experiments were conducted in accordance to OECD Guideline 203 and under GLP compliance. Based on the intrinsic properties of the used substances, Water Accommodated Fractions (WAFs) were prepared for testing. Physico-chemical parameters (i.e. water temperature, pH and dissolved oxygen concentration (DOC)) were recorded daily throughout the test duration of 96 h.
The toxic effects of the magnesium sulfonate read-across substance(CAS 71786-47-5) were experimentally determined using Pimephales promelas (Fathead minnows) as test organisms (Ward, 1993). Juvenile animals were held for a minimum of 14 days prior to testing and were free of sickness, injuries and abnormalities at the start of the test. 100, 300 and 1000 mg/L WAF loading rates were used as test concentrations. A control group was included, however, no reference substance testing was performed. Control mortality did not exceed the test validity criterion (i.e. < 10 % mortality in controls). No mortality or signs of toxicity were noted in either the control or WAF treatments throughout the exposure time of 96 h. Therefore, the NOELR (96h) is reported as 1000 mg/L WAF, the LL50 (96h) is > 1000 mg/L WAF. Statistical analysis of the data was not warranted on the basis that no mortality occurred in this study.
In a 96-hour acute toxicity study, juvenile Rainbow trouts (Oncorhynchus mykiss) were exposed to the calcium sulfonate read-across substance (CAS 115733-09-0) at nominal concentrations of 0 (control group) and 100 mg/L WAF loading rate under semi-static conditions (Goodband, 2005). No mortalities and no sublethal effects were noted at the highest tested concentration, thus the LL50 (96h) is reported to be > 100 mg/L WAF with a corresponding NOELR of 100 mg/L WAF.
Acute toxicity to saltwater fish
Cyprinodon variegatus (Shepshead minnow) was used as saltwater representative fish in an experiment in order to determine the toxicity potential of the magnesium sulfonate read-across substance (CAS 71786-47-5) (Nicholson, 1986). The acclimatisation period was about 13 days and the biomass loading rate was 0.056 g/L. A control group was included and a single concentration of 10000 mg/L WAF was applied (limit test). The exposure time was 96 h. Sodium lauryl sulfate was used as reference substance, revealing a LC50 (96h) of 1.2 mg/L. Neither in the control nor in any of the treatment groups were mortality or signs of toxicity recorded. Therefore, the LL50(96h) is > 10000 mg/L WAF with a corresponding NOELR of 10000 mg/L WAF. No statistical analysis of data was warranted due to the fact that the test substance was found to be non-toxic under the applied conditions.
Conclusion:
No toxic effects observed in all acute fish studies even at the highest concentration levels tested. The toxicity data available for several acute fish studies (quantified as Water Accommodated Fractions (WAFs)) demonstrate that the substance is not toxic to fish even at the highest test substance concentrations tested (10000 mg/L). The weight-of-evidence indicate that the lower NOECs for O. mykiss are not an indicator of toxicity per se, but are the result of dose selection.Long-term investigations are not triggered based on the observations in acute tests.
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