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EC number: 603-923-2 | CAS number: 135590-91-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 10 Dec 1991 - 02 Jun 1992
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 106 (Adsorption - Desorption Using a Batch Equilibrium Method)
- GLP compliance:
- yes
- Type of method:
- batch equilibrium method
- Media:
- soil
- Details on study design: HPLC method:
- EQUIPMENT
- Apparatus: - Analytical monitoring:
- yes
- Details on matrix:
- see table below
- Details on test conditions:
- Test solutions:
Using a stock solution of the test substance (1 g/1 in acetonitrile) the following dilutions in
autoclaved 0.01 M CaCl2-solution were prepared (nom. values): 5 mg/1 for kinetics; 5, 1, 0.2 and
0.05 mg/1 for adsorption/desorption. Confirmation of the content using HPLC: 4.9 mg/1 for kinetics;
5.1, 0.7, 0.15 and 0.05 mg/1 for adsorption/desorption. The dilutions were prepared under laminar
flow conditions. - Computational methods:
- - Adsorption and desorption coefficients (Kd):The adsorption and desorption parameters were calculated from measurements by the application of the Freundlich approach.
- Type:
- Koc
- Value:
- >= 486 - <= 823
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 106 (Adsorption - Desorption Using a Batch Equilibrium Method)
- Qualifier:
- according to guideline
- Guideline:
- other: USEPA (= EPA) Subdiv. N (1982)
- Principles of method if other than guideline:
- Study design reflects both EPA and OECD (Section 106, 1981;2 proposed Section 1063, 19964) guidelines.
- GLP compliance:
- yes
- Type of method:
- batch equilibrium method
- Media:
- soil
- Radiolabelling:
- yes
- Analytical monitoring:
- yes
- Type:
- Koc
- Value:
- >= 678 - <= 738
Referenceopen allclose all
Findings:
The KOC-values along with key soil parameters are summarized in the table below:
No formation of degradation products was observed in the course of the study. The desorption coefficients were slightly higher than the adsorption coefficients, indicating a hysteresis effect for the adsorption/desorption process with a possibly irreversible binding of the substance to the soil matrix.
Summary of adsorption coefficients of AE F107892
Soil |
pH |
Organic Carbon |
Kf, ads |
KOC |
1/n |
Silt Loam (SLH) |
6.2 |
1.10 |
7.08 |
644 |
0.99 |
Sandy Loam (SLV) |
5.8 |
1.13 |
6.71 |
593 |
1.20 |
Sand (S2.1) |
5.0 |
1.17 |
5.68 |
486 |
1.20 |
Loamy Sand (LS2.2) |
5.0 |
2.91 |
23.96 |
823 |
1.23 |
Loamy Sand (LSN) |
7.1 |
0.89 |
5.16 |
580 |
1.20 |
Findings:
The equilibrium in the soil/water system was established after approx. 8 hours.
AE F107892 was found to be stable under sterile conditions with above 90% of the residue recovered in the soil and water portions after 72 hours identified as AE F107892.
The calculated adsorption constants KF(ads) of the Freundlich isotherm along with the Freundlich exponent 1/n are summarized in the table below:
Summary of adsorption coefficients of AE F107892
Soil |
pH |
Organic Carbon |
Kf, ads |
KOC |
1/n |
Sand (NC, US) |
5.0 |
0.49 |
3.16 |
648 |
0.96 |
Sandy Clay Loam (ND, US) |
7.4 |
2.70 |
19.9 |
738 |
0.96 |
Conclusion:
The results indicate a medium to well adsorption to all soils. Mefenpyr-diethyl AE F107892 is therefore of low mobility in soil. Consequently, there is a reduced risk of leaching into deeper layers of soil.
Description of key information
The Koc (adsorption) at 20 °C was determined to be in the range of 486 to 823 mL/g (batch equilibrium method, OECD 106).
Key value for chemical safety assessment
- Koc at 20 °C:
- 486
Additional information
The adsorption/desorption behaviour of the substances was tested in a guideline study following OECD guideline 106 (1992). The test was conducted with five different soils (Silt Loam, Sandy Loam, Sand, and two types of Loamy Sand). The Koc values ranged from 486 to 823 depending on soil type.
Comparable results were determined in a supporting study following OECD guideline 106 investigating the adsorption/desorption behaviour in sand and sandy clay loam (1997). The determined Koc values were 648 mL/g in sand and 738 mL/g in sandy clay loam respectively.
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