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EC number: 273-734-4 | CAS number: 69012-34-6 By-product from open-hearth steelmaking. Consists of oxides of calcium, iron, silicon and vanadium.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
Based on available water solubility data, "Slags, steelmaking, vanadium" is rather inert with respect to the dissolution of slag components in water with the exception of slightly soluble vanadium. Aluminum, magnesium, manganese, molybdenum and zinc dissolved at detectable concentrations but these concentrations are neglectable in any physiological meaning. Thus, read-across of skin sensitisation data from soluble tri-, tetra-, and pentavalent vanadium substances is justified.
The studies by Haferkorn (2010a,b,c) are considered key studies on skin sensitisation and are used for classification. Soluble tri-tetra, and pentavalent vanadium substances failed to elicit any skin sensitising response in sensitisation studies according to Magnusson and Kligman (OECD 406). Positive human experience with any vanadium substance have not been reported. Thus, these negative results are read-across to Slags, steelmaking, vanadium. Therefore, no classification and labelling according to directive 67/548/EEC and to regulation (EC) 1272/2008 is required.
Migrated from Short description of key information:
Slags, steelmaking, vanadium is considered inert with the exception of slightly soluble vanadium. Soluble tri-, tetra- and pentavalent vanadium substances did test negative (i.e. not sensitising) in sensitisation studies according to Magnusson and Kligman (OECD 406). A justification for using the Magnusson and Kligman design instead of the LLNA is provided as an attached document below.
Slags, steelmaking, vanadium is considered to have no sensitisation potential.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
- Migrated from Short description of key information:
Exposure to slags, steelmaking, vanadium has not been reported to induce immune responses in vanadium industry workers, and occupational asthma or reduced lung function have not been diagnosed in vanadium producing facilities. Furthermore, exposure via inhalation is not expected to this transported intermediate under normal operating conditions.
Justification for classification or non-classification
According to the outcome of sensitisation studies with soluble vanadium forms according to Magnusson and Kligman, it can be concluded that "slags, steelmaking , vamadium" is considered to have no sensitisation potential and must not be classified and labelled according to directive 67/548/EEC and to Regulation (EC) 1272/2008.
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