Registration Dossier
Registration Dossier
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EC number: 247-569-3 | CAS number: 26266-58-0
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No effects up to the limit of water solubility for Daphnia magna (OECD 211); read-across
Key value for chemical safety assessment
Additional information
No studies are available on the long-term toxicity of Anhydro-D-glucitol trioleate (CAS No. 26266-58-0) to aquatic invertebrates. The assessment was, therefore, based on a study conducted with the structurally similar category member Sorbitan, (Z)-9-octadecenoate (2:3) (CAS No. 8007-43-0) as part of a read-across approach. This is in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5. Grouping of substance and read across approach. Both substances are Sorbitan di- or triesters of unsaturated C18 fatty acids. Due to the similarity of the two substances in terms of physico-chemical properties and molecular structure, their toxicity to aquatic invertebrates is expected to be comparable.
The key study conducted with Sorbitan, (Z)-9-octadecenoate (2:3) (CAS No. 8007-43-0) was performed according to OECD guideline 211 and GLP (Parr, 2013). The test organism Daphnia magna was exposed to the test substance in a semi-static system for 21 days, at nominal concentrations of 10, 18, 32, 56 and 100 % v/v. Since no effects occurred, the concentration 100 % v/v was determined to be the NOEC. The time-weighted mean measured test concentration corresponding to the 100 % v/v nominal test concentration was 0.11 mg/L.
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