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EC number: 242-171-6 | CAS number: 18293-82-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Biodegradation in water (screening tests):36% in 28 days (9.97 mg/l) and 47% in 28 days (20.1 mg/l) % in 28 days (OECD 301B), read-across from a structurally related substance. No significant biodegradation of the silanol hydrolysis product is expected.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
Table: Ready biodegradation data for substances within the relevant sub-class I-2 of chemicals
CAS |
Name |
Main code |
Readily biodegradable? Yes/no |
Result: Biodegradation after 28 days (%) |
Guideline |
Test type |
Klimisch code |
Corrected % biodegradation once alkoxy/acetoxy biodegradation is accounted for[1] |
001066-40-6 |
Hydroxytrimethylsilane |
I-2 |
No |
0% |
OECD 310 and ISO Guideline N 14593 |
CO2 |
1 |
0 |
013154-25-1 |
Chlorotri(3-methyl-propyl)silane |
I-2-M-C |
No |
0% |
OECD 301B |
CO2 |
1 |
0 |
139147-73-2 |
Silane, dichlorodicyclopentyl- |
I-2-D-C |
No |
0.80% |
OECD 301D |
BOD |
2 |
1 |
000098-12-4 |
Cyclohexyltrichlorosilane |
I-2-D-C |
No |
0% |
OECD 301C |
BOD |
1 |
0 |
000124-70-9 |
Dichloro(methyl)(vinyl)silane |
I-2-D-C |
No |
-6.78% (0%) |
OECD 301 A |
DOC |
1 |
0 |
017865-32-6 |
Cyclohexyldimethoxymethylsilane |
I-2-D-Me-H |
No |
15-17% |
OECD 301D |
BOD |
1 |
-5 |
126990-35-0 |
Dicyclopentyldimethoxysilane |
I-2-D-Me-M |
No |
12% |
OECD 301C |
BOD |
1 |
-5 |
None46 |
t-butoxycyclopentyldimethoxysilane |
I-2-D-Me-M |
No |
15% BOD; 25% TOC; 100% GC |
OECD 301C |
BOD/DOC |
1 |
7 |
017689-77-9 |
Triacetoxyethylsilane |
I-2-T-A |
Yes |
74% in 21 days |
EC C4-A |
DOC |
1 |
-1 |
017980-47-1 |
Triethoxyisobutylsilane |
I-2-T-Et-M |
Yes |
75% |
OECD 301D |
BOD |
1 |
15 |
002943-75-1 |
Triethoxyoctylsilane |
I-2-T-Et-M |
No |
31.50% |
OECD 301D |
BOD |
1 |
-11 |
035435-21-3 |
Triethoxy(2,4,4-trimethylpentyl)silane |
I-2-T-Et-M |
No |
13% |
OECD310 |
CO2 |
1 |
-30 |
016415-13-7 |
Triethoxyhexadecylsilane |
I-2-T-Et-S |
No |
43% by BOD; 74% by HPLC |
MITI |
BOD |
1 |
16 |
001067-25-0 |
Trimethoxypropylsilane |
I-2-T-Me-H |
No |
54% |
Annex V C4-A |
DOC |
1 |
4 |
087135-01-1 |
1,6-Bis(trimethoxysilyl)hexane |
I-2-T-Me-H |
yes but not meeting 10-day window |
74% |
OECD 301B |
CO2 |
1 |
24 |
None45 |
Mixture of 1,1- and 1,2-bis(trimethoxysilyl)ethane |
I-2-T-Me-H |
Yes |
93% BOD; 78% TOC; 100% GC (ethanol?) |
"Biodegradation study of chemical substances by microorganismsand the like"[2] |
BOD/DOC |
1 |
18 |
018395-30-7 |
Isobutyl(trimethoxy)silane |
I-2-T-Me-H |
No |
36 - 47% |
OECD 301B |
CO2 |
1 |
4 |
002768-02-7 |
Trimethoxyvinylsilane |
I-2-T-Me-H |
No |
51% |
OECD 301F |
BOD |
1 |
-9 |
142877-45-0 |
Silane, trimethoxy(1,1,2-trimethylpropyl)- |
I-2-T-Me-S |
No |
31% |
OECD 301D |
BOD |
1 |
-2 |
[1]The negative values in this column are where the biodegradation rate observed in the test is less than that expected assuming only alkoxy/acetoxy parts biodegrade. This could be due to low solubility of parent substance or low rates of hydrolysis. These values should in effect be considered as zero.
[2]Stipulated in "Testing Method for New Chemical Substances etc." (Kanhogyo No.5, Yakuhatsu 615, 49Kikyoku No.392, July 13, 1974)
In the study with isobutyl(trimethoxy)silane (CAS 18395-30-7), the substance attained 36% and 47% biodegradation in 28 days at 9.97 mg/l and 20.1 mg/l, respectively.
Isobutyl(trimethoxy)silane (CAS 18395-30-7) hydrolyses within the timescale of the ready biodegradation study to(2 -methylpropyl)silanetrioland methanol.The biodegradation observed in the study is attributable to the biodegradation of the methanol hydrolysis product. Methanol is readily biodegradable (OECD, 2004). No significant biodegradation is expected for the silanol hydrolysis product.
The study was conducted according to OECD 301B and is considered to be reliable. This is selected as the key study.
The study is considered to be reliability 1 (reliable without restrictions); the read across of the result is considered to be reliability 2 (reliable with restrictions).
References:
OECD (2004): SIDS Initial Assessment Report for SIAM 19, Berlin, Germany, 18-20 October 2004, Methanol, CAS 67-56-1.
PFA, 2013f, Peter Fisk Associates, Biodegradation Main Analogue Group report, PFA.300.005.007
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