Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 235-060-9 | CAS number: 12064-62-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Density
Administrative data
Link to relevant study record(s)
- Endpoint:
- relative density
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 07 June 2016 - 12 July 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.3 (Relative Density)
- Deviations:
- yes
- Remarks:
- The purging time was less than 20 minutes for the first and second assays. Therefore, the first runs were not taken into account. This deviation was not considered to have affected the quality of the results obtained.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 109 (Density of Liquids and Solids)
- Deviations:
- yes
- Remarks:
- The purging time was less than 20 minutes for the first and second assays. Therefore, the first runs were not taken into account. This deviation was not considered to have affected the quality of the results obtained.
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- pycnometer method
- Key result
- Type:
- relative density
- Density:
- ca. 7.983
- Temp.:
- 19.9 °C
- Remarks on result:
- other: Mean value of two assays (assay No.1: 8.094, assay No.2: 7.871)
- Conclusions:
- The relative density of gadolinium oxide was determined according to EU A.3 method and OECD test guideline 109 in compliance with GLP using a gas comparison pycnometer. The relative density of the test item was determined to be 7.983 ± 0.123 at 19.9°C. The deviation from the guideline which was observed during the study is not considered to have affected the outcome of the study, since the affected runs were not taken into account for determination of the final result. Consequently, the results of the study are considered reliable without restrictions (Klimisch 1).
- Endpoint:
- density, other
- Remarks:
- density
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Principles of method if other than guideline:
- Data obtained from the peer reviewed CRC Handbook of Chemistry and Physics. No information given on methodology.
- GLP compliance:
- no
- Type of method:
- other: no data
- Type:
- density
- Density:
- 7.41 g/cm³
- Conclusions:
- According to the peer reviewed CRC Handbook of Chemistry and Physics, gadolinium oxide has a density of 7.41 g/cm3.
Referenceopen allclose all
Two independent measurements at 20.2°C (assay No. 1) and 19.6°C (assay No. 2) were done. Runs 1, 2 and 3 of assay No. 1 and runs 1, 2, 3 and 4 of assay No. 2 were not taken into account because they did not comply with the quality criterion. A longer stabilisation time of the pressure was needed to obtain three consequent runs complying with the quality criterion.
The two assays resulted in relative densities of 8.094 ± 0.003 and 7.871 ± 0.001, respectively. The mean relative density was thus 7.983 ± 0.123 at 19.9°C.
Reference volume (Va) was 79.250 cm3.
Volume of sample cell holder (Vc) was 27.636 cm3.
Test item sample weight was 8.1766 g and 8.3251 g in assay No. 1 and 2, respectively.
The measurements are described in the table in the next section.
Description of key information
The relative density of gadolinium oxide was determined in a GLP study (Klimisch 1, Demangel, 2016) according to the EU A.3 method and OECD test guideline 109 using a gas comparison pycnometer. The relative density of the test item was determined to be 7.983 ± 0.123 at 19.9°C. This value is considered as the key value for gadolinium oxide.
Key value for chemical safety assessment
- Relative density at 20C:
- 7.983
Additional information
In the key study of Demangel (2016) performed according to the EU A.3 method and OECD test guideline 109, a deviation from the guideline was observed during the study. However, since the affected runs were not taken into account for determination of the final result, the deviation is not considered to have affected the quality or the interpretation of the results obtained, hence, the results of the study are considered reliable without restrictions (Klimisch 1).
In the CRC Handbook of Chemistry and Physics (97th edition, 2016-2017) a density of 7.41 g/cm3 is reported for gadolinium oxide. The difference in the composition of the impurity content of the test items used in the key study and the study from which the handbook value was taken, would most likely explain the small but acceptable difference in the relative densities obtained in both studies. In the presence of a fully documented study, handbook data are recommended to be considered as supporting information.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.