Registration Dossier
Registration Dossier
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EC number: 224-314-4 | CAS number: 4303-67-7
Vapour pressure
Administrative data
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 18 Sep 2014 - 25 Sep 2014
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: The study was done in accord with EU guidance and was in compliance with GLP criteria.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 014
- Report date:
- 2014
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7950 (Vapor Pressure)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- effusion method: by loss of weight or by trapping vaporisate
Test material
- Reference substance name:
- Laurylimidazole
- IUPAC Name:
- Laurylimidazole
- Test material form:
- other: Liquid
- Details on test material:
- - Name of test material (as cited in study report): MTDID 13999
- Analytical purity: 99.0%
- Storage condition of test material: At room temperature in the dark
Constituent 1
Results and discussion
Vapour pressure
- Temp.:
- 20 °C
- Vapour pressure:
- 0.009 Pa
Applicant's summary and conclusion
- Conclusions:
- The vapor pressure of laurylimidazole is 0.0088 Pa at 20°C.
- Executive summary:
The vapor pressure of the test substance was determined by the isothermal thermogravimetric effusion method. The weight loss of the sample was measured at 4 isothermal points between 90 and 120°C. Weight loss rate at each temperature was converted to vapor pressure and entered into linear regression analysis vs. temperature. The resulting equation was log P(T) = -4327 ×1/T + 12.70 (r = 0.9994). The test was done according to EU Method A.4 “Vapour pressure” and OECD 104 “Vapour Pressure Curve” and in accord with GLP guidelines, and the thermogravimetric analysis method is particularly suited to substances of low vapor pressure (10E-10 Pa to 1 Pa). Therefore this study is classified as reliable without restriction.
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