Summary of Classification and Labelling
Harmonised classification - Annex VI of Regulation (EC) No 1272/2008 (CLP Regulation)
General Information
Index Number EC / List no.

EC: European Community number/ List no.: List number assigned by ECHA.

List Numbers are purely technical identifiers for processing a submission via REACH-IT. More information: https://echa.europa.eu/information-on-chemicals/registered-substances/information

CAS Number International Chemical Identification
612-051-00-1 202-974-4 101-77-9 4,4'-diaminodiphenylmethane
4,4'-methylenedianiline

ATP Inserted / Updated: CLP00 This field indicates when an entry in Annex VI to CLP has been inserted and/or updated with an Adaptation to Technical Progress (ATP) to the CLP Regulation.
CLP Classification (Table 3)
Classification Labelling Specific Concentration limits, M-Factors Notes
Hazard Class and Category Code(s) Hazard Statement Code(s) Hazard Statement Code(s) Supplementary Hazard Statement Code(s) Pictograms, Signal Word Code(s)
Skin Sens. 1 H317 H317 GHS09
GHS08
GHS07
Dgr
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 ** H370 **
STOT RE 2 * H373 ** H373 **
Aquatic Chronic 2 H411 H411

Signal Words Pictograms
Danger
GHS09
Environment
GHS08
Health hazard
GHS07
Exclamation mark
Seveso III Data
Disclaimer: Please note that some of the substances covered by the Seveso Directive can belong to more than one Seveso categories. It will be up to the users to decide whether their substance or mixture fall in one or in more of these classification categories depending on the tonnage bands and the concentrations.
Please also note that ECHA is not an authority for the Seveso Directive and that the Seveso categorisation below is provided for information only. The Seveso III Directive (Directive 2012/18/EU repealing Directive 96/82/EC (Seveso II) from 1 June 2015) is the only authentic legal reference and that the information in this inventory does not constitute legal advice. For further information on Seveso, please ask your national authority.

Seveso Data
Seveso Substance Seveso Categories
Tak H3
E2
Notified classification and labelling
General Information
EC / List no.

EC: European Community number/ List no.: List number assigned by ECHA.

List Numbers are purely technical identifiers for processing a submission via REACH-IT. More information: https://echa.europa.eu/information-on-chemicals/registered-substances/information

Name CAS Number
The CAS number associated with this substance in the EC Inventory and/or REACH-IT is reported here. In some cases, e.g. for differently hydrated forms of the same substance, alternative CAS numbers have been notified. In those cases, the additional CAS numbers are published in the column “additional notified information” below.
202-974-4 4,4'-methylenedianiline 101-77-9

Notified classification and labelling according to CLP criteria
Classification Labelling Specific Concentration limits, M-Factors Notes Classification affected by Impurities / Additives

This check appears when a notifier has indicated that an impurity or an additive present in the substance impacts the notified classification. ECHA cannot reveal the identity of the impurity/additive or determine the exact impact it has on the classification.

Additional Notified Information

State/form: The notified state/form of the substance for all notifications classifying in this manner is reported under this link. Additional CAS number(s): Occasionally, a notification contains a different CAS number than the one reported under the general information section above. In those cases, all different notified CAS numbers associated with the aggregated classification are reported under this link. IUPAC name(s): Publicly available IUPAC names from all notifications classifying in this manner are reported under this link.

Number of Notifiers

This number indicates how many companies notified this classification. All members of a REACH registration joint submission and all participants in a group of manufacturers/importers who notified are counted. The grouping is done automatically with no manual verification.

Joint Entries

This check appears when a classification comes from a lead dossier of a REACH registration joint submission. When a member submits a classification separately under Article 11(3) of REACH (opt-out), this classification is displayed separately and not marked as a joint entry.

Hazard Class and Category Code(s) Hazard Statement Code(s) Hazard Statement Code(s) Supplementary Hazard Statement Code(s) Pictograms, Signal Word Code(s)
Skin Sens. 1 H317 H317 GHS09
GHS08
GHS07
Dgr
M(Chronic)=0
IUPAC Names 16 yes View details
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 (liver, retina) H370
STOT RE 2 H373 (liver) H373
Aquatic Chronic 2 H411 H411
Acute Tox. 3 H301 H301 GHS09
GHS08
GHS06
GHS07
Dgr
M=1
M(Chronic)=10
IUPAC Names 10 yes View details
Skin Sens. 1 H317 H317
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 (liver, retina) H370
STOT RE 2 H373 (liver) H373
Aquatic Acute 1 H400 H400
Aquatic Chronic 1 H410 H410
Skin Sens. 1 H317 H317 GHS09
GHS08
GHS07
Dgr
State/Form
IUPAC Names
302 View details
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 H370
STOT RE 2 H373 H373
Aquatic Chronic 2 H411 H411
Skin Sens. 1 H317 H317 GHS09
GHS08
GHS07
Dgr
M(Chronic)=10
State/Form
IUPAC Names
66 View details
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 (Liver, Eye (ret...) H370
STOT RE 2 H373 (Liver) H373
Aquatic Chronic 2 H411 H411
Skin Sens. 1 H317 H317 GHS08
Dgr
IUPAC Names 47 View details
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 (Not provided) H370
STOT RE 2 H373 (Not provided) H373
Aquatic Chronic 2 H411 H411
Acute Tox. 4 H302 H302 GHS09
GHS08
GHS07
Dgr
30 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 (Not available) H370
STOT RE 2 H373 (Not available) H373
Aquatic Chronic 2 H411 H411
Skin Sens. 1 H317 H317 GHS09
GHS08
GHS07
Dgr
IUPAC Names 27 View details
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 (liver, retina) H370
STOT RE 2 H373 (liver) H373
Aquatic Chronic 2 H411 H411
Acute Tox. 3 H301 H301 GHS09
GHS08
GHS06
Dgr
State/Form
16 View details
Skin Sens. 1 H317 H317
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 (not specified)  
STOT RE 2 H373 (not specified)  
Aquatic Chronic 2 H411 H411
Skin Sens. 1 H317 H317 GHS09
GHS08
GHS07
Dgr
State/Form
IUPAC Names
9 View details
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 (unknown) H370
STOT RE 2 H373 (unknown) H373
Aquatic Chronic 2 H411 H411
Skin Sens. 1 H317 H317 GHS09
GHS08
Dgr
State/Form
IUPAC Names
6 View details
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 (not identified) H370
STOT RE 2 H373 (not identified) H373
Aquatic Chronic 2 H411 H411
Skin Sens. 1 H317 H317 (H317) GHS09
GHS08
GHS07
Dgr
IUPAC Names 4 View details
Muta. 2 H341 H341 (H341)
Carc. 1B H350 H350 (H350)
STOT SE 1 H370 (eyes, liver, ca...) H370 (H370)
STOT RE 2 H373 (eyes, liver, ca...) H373 (H373)
Aquatic Chronic 2 H411 H411 (H411)
Skin Sens. 1 H317 H317 GHS09
GHS08
GHS07
Dgr
Note E
State/Form
3 View details
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 H370
STOT RE 2 H373 H373
Aquatic Chronic 2 H411 H411
Skin Sens. 1 H317 H317 GHS09
GHS08
GHS07
Dgr
IUPAC Names 2 View details
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 (Several) H370
STOT RE 2 H373 (Several) H373
  H411
Skin Sens. 1 H317 H317 GHS09
GHS08
Dgr
State/Form
IUPAC Names
1 View details
Muta. 2 H341  
Carc. 1B H350 H350
STOT SE 1 H370 (Affected organ) H370
Aquatic Chronic 2 H411 H411

Number of Aggregated Notifications: 14