PBT assessment list

ECHA’s persistence, bioaccumulation and toxicity (PBT) assessment list includes the substances undergoing a PBT/vPvB assessment that have been brought for discussion to ECHA’s PBT Expert Group.

Explanatory note

Inclusion in the list means that an informal hazard assessment for PBT/vPvB properties either is under development or has been completed since February 2013.

For each substance, the table shows the assessing or evaluating Member State (submitter), the outcome from the assessment, and the date of the latest update to the list entry.

Other process details and hazard assessment outcome documents are also available and can be accessed through the ‘Details’ icon.

One possible outcome of such an assessment is that a substance is considered not to have PBT/vPvB properties.

If the outcome is that the substance is considered to have PBT/vPvB properties, confirmation through the formal risk management and decision-making processes is needed before any regulatory action can be taken due to these properties.

The intentions of authorities to submit a dossier to the formal REACH and CLP processes are notified through the Registry of Intentions. All biocidal active substances have to undergo a formal PBT assessment. You can see the status of biocides assessments on the Biocidal Active Substances page.

Disclaimer

The information and views set out in the PBT assessment list and in the hazard assessment outcome documents are those of the evaluating authority and do not necessarily reflect the position or opinion of the other Member States or ECHA. Neither ECHA nor the evaluating authority nor any person acting on either of their behalves may be held liable for the use, which may be made of the information contained therein. Statements made or information contained in the documents are without prejudice to any formal regulatory activities that ECHA or the Member States may initiate at a later stage. PBT assessments and their outcomes are compiled on the basis of information available by the date of the publication of the document.

Last updated 11 April 2024. Database contains 231 unique substances/entries.

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Latest update:

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Date of hazard assessment:

Showing 1 - 100 of 236 results.

Substance name	EC / List no	CAS no	Authority	Outcome	Latest update
Octamethyltrisiloxane	203-497-4	107-51-7		Under development	19-Mar-2024	Details
2,2',6,6'-tetra-tert-butyl-4,4'-methylenediphenol	204-279-1	118-82-1	Austria	Under development under SEV	27-Mar-2019	Details
3,7,11-trimethyldodeca-1,6,10-trien-3-ol,mixed isomers	230-597-5	7212-44-4	Austria	not PBT not vPvB	05-Jun-2015	Details
6,6'-di-tert-butyl-4,4'-thiodi-m-cresol	202-525-2	96-69-5	Austria	Under development under SEV	05-Jun-2015	Details
Bis(4-chlorophenyl) sulphone	201-247-9	80-07-9	Austria	vPvB	17-Dec-2020	Details
Bis(4-chlorophenyl) sulphone	201-247-9	80-07-9	Austria	vPvB	08-Feb-2024	Details
N-(1,4-dimethylpentyl)-N'-phenylbenzene-1,4-diamine	221-374-3	3081-01-4	Austria	Under development under SEV	05-Jun-2015	Details
Reaction mass of (2S,5R)-2-tert-butyl-5-methyl-2-propyl-2,5-dihydrofuran and (2S,5S)-2-tert-butyl-5-methyl-2-propyl-2,5-dihydrofuran	700-103-7	-	Austria	Under development	05-Jun-2015	Details
Reaction products of acetic anhydride and 1,5,10-trimethyl-1,5,9-cyclodecatriene	482-330-9	144020-22-4	Austria	Under development	05-Jun-2015	Details
Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate	222-020-0	3319-31-1	Austria	Under development under SEV	05-Jun-2015	Details
1-hydroxy-4-[[4-[(methylsulphonyl)oxy]phenyl]amino]anthraquinone	216-475-4	1594-08-7	Belgium	Under development under SEV	02-Jun-2020	Details
2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(4-chloro-2,5-dimethoxyphenyl)-3-oxobutyramide]	226-939-8	5567-15-7	Belgium	not PBT not vPvB	11-Dec-2015	Details
2,4,6-tri-tert-butylphenol	211-989-5	732-26-3	Belgium	PBT vPvB	08-Feb-2024	Details
2,4-di-tert-butylphenol	202-532-0	96-76-4	Belgium	not PBT not vPvB	01-Apr-2015	Details
2,6-di-tert-butylphenol	204-884-0	128-39-2	Belgium	not PBT not vPvB	01-Apr-2015	Details
2,9-dimethylanthra[2,1,9-def:6,5,10-d'e'f']diisoquinoline-1,3,8,10(2H,9H)-tetrone	226-866-1	5521-31-3	Belgium	inconclusive	10-Aug-2023	Details
4,4'-(1,3-phenylene-bis(1-methylethylidene))bisphenol	428-970-4	13595-25-0	Belgium	postponed	28-Apr-2022	Details
A mixture of: O,O-di(1-methylethyl)trithio-bis-thioformate; O,O-di(1-methylethyl)tetrathio-bis-thioformate; O,O-di(1-methylethyl)pentathio-bis-thioformate ROBAC AS/100	403-030-6	137398-54-0	Belgium	not PBT not vPvB	30-Jun-2021	Details
Ammonium salts of mono- and bis[3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl and/or poly (substituted alkene)] phosphate	700-403-8	-	Belgium	PBT vPvB	07-Sep-2023	Details
Amphoteric Fluorinated Surfactant	-	-	Belgium	PBT vPvB	07-Aug-2023	Details
Mono- and/or di- and/or tri(1-phenylethyl)-m-cresol and p-cresol	700-427-9	-	Belgium	postponed	17-Mar-2022	Details
N,N'-bis(1,4-dimethylpentyl)-p-phenylenediamine	221-375-9	3081-14-9	Belgium	not PBT	24-Jan-2019	Details
N,N'-dithiodi-o-phenylenedibenzamide	205-201-9	135-57-9	Belgium	not PBT not vPvB	28-Oct-2021	Details
N-[4-[(9,10-dihydro-4-hydroxy-9,10-dioxo-1-anthryl)amino]phenyl]acetamide	267-636-0	67905-17-3	Belgium	Under development under SEV	02-Jun-2020	Details
o-(p-isocyanatobenzyl)phenyl isocyanate	227-534-9	5873-54-1	Belgium	not PBT not vPvB	21-Jul-2015	Details
Perfluamine	206-420-2	338-83-0	Belgium	Under development under SEV	03-Mar-2021	Details
Perylene-3,4:9,10-tetracarboxydiimide	201-344-6	81-33-4	Belgium	inconclusive	10-Aug-2023	Details
reaction mass of 2,2,3,3,5,5,6,6-octafluoro-4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)morpholine and 2,2,3,3,5,5,6,6-octafluoro-4-(heptafluoropropyl)morpholine	473-390-7	-	Belgium	vPvB	22-Jun-2022	Details
Reaction mass of 2,6-di-tert-butylphenol and 2,4,6-tri-tert-butylphenol	907-745-9	-	Belgium	PBT vPvB	03-Mar-2021	Details
S-(tricyclo(5.2.1.0'2,6)deca-3-en-8(or 9)-yl O-(isopropyl or isobutyl or 2-ethylhexyl) O-(isopropyl or isobutyl or 2-ethylhexyl) phosphorodithioate X4261	401-850-9	255881-94-8	Belgium	PBT	17-Aug-2021	Details
Methoxychlor	200-779-9	72-43-5	Commission	PBT	02-Apr-2020	Details
Octamethylcyclotetrasiloxane	209-136-7	556-67-2	Commission	PBT vPvB	07-Aug-2015	Details
Dichloro(dimethyl)silane	200-901-0	75-78-5	Czech Republic	not PBT not vPvB	01-Apr-2015	Details
1,2-benzenedicarboxylic acid, di-C10-12-branched alkyl esters	700-989-5	-	Denmark	not PBT not vPvB	15-Feb-2021	Details
1,2-Benzenedicarboxylic acid, di-C11-14-branched alkyl esters, C13-rich	271-089-3	68515-47-9	Denmark	not PBT	23-Jan-2020	Details
2,2',6,6'-tetrabromo-4,4'-isopropylidenediphenol	201-236-9	79-94-7	Denmark	Under development under SEV	01-Apr-2015	Details
Diundecyl phthalate, branched and linear	287-401-6	85507-79-5	Denmark	not PBT	20-Jan-2020	Details
Oligomerisation and alkylation reaction products of 2-phenylpropene and phenol show/hide Phenol, methylstyrenated EC / List no: 270-966-8 \| CAS no: 68512-30-1	700-960-7	-	Denmark	Under development under SEV	01-Apr-2015	Details
4-(1,1,3,3-tetramethylbutyl)phenol	205-426-2	140-66-9	ECHA	postponed	10-Mar-2022	Details
Benzyltoluene	248-654-8	27776-01-8	ECHA	Under development	01-Apr-2015	Details
Chlorpyrifos	220-864-4	2921-88-2	ECHA		17-Dec-2020	Details
Creosote oil, acenaphthene fraction A complex combination of hydrocarbons produced by the distillation of coal tar and boiling in the range of approximately 240°C to 280°C (464°F to 536°F). Composed primarily of acenaphthene, naphthalene and alkyl naphthalene.	292-605-3	90640-84-9	ECHA	Under development	01-Apr-2015	Details
Dibutyl phthalate	201-557-4	84-74-2	ECHA	postponed	10-Mar-2022	Details
Fatty acids, C18-unsatd., dimers, 2-ethylhexyl esters	500-204-4	68334-05-4	ECHA	Under development	27-Mar-2019	Details
Oligomerisation products of 3-isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate, isocyanurate type	931-312-3	-	ECHA	Under development	27-Mar-2019	Details
Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts	283-392-8	84605-29-8	ECHA	Under development	27-Mar-2019	Details
Tamoxifen	234-118-0	10540-29-1	ECHA	postponed	17-Mar-2022	Details
Tar acids, xylenol fraction The fraction of tar acids, rich in 2,4- and 2,5-dimethylphenol, recovered by distillation of low-temperature coal tar crude tar acids.	284-895-5	84989-06-0	ECHA	Under development	27-Mar-2019	Details
Tributyltin chloride	215-958-7	1461-22-9	ECHA	postponed	17-Mar-2022	Details
Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate)	224-235-5	4259-15-8	ECHA	Under development	27-Mar-2019	Details
4,4'-methylenediphenyl diisocyanate	202-966-0	101-68-8	Estonia	not PBT not vPvB	28-Jan-2019	Details
Reaction mass of 4,4'-methylenediphenyl diisocyanate and o-(p-isocyanatobenzyl)phenyl isocyanate / methylene diphenyl diisocyanate	905-806-4	-	Estonia	not PBT not vPvB	28-May-2021	Details
Shale oil bitumen	447-780-2	-	Estonia	inconclusive	22-Jun-2022	Details
(ethoxymethoxy)cyclododecane	261-332-1	58567-11-6	Finland	not PBT not vPvB	07-Aug-2015	Details
1,2,3,4-Tetrahydro-6-(1-phenylethyl)naphthalene	400-370-7	6196-98-1	Finland	Under development under SEV	08-Apr-2021	Details
Decahydronaphthalene	202-046-9	91-17-8	Finland	Under development under SEV	01-Apr-2015	Details
Methylcyclohexane	203-624-3	108-87-2	Finland	not PBT not vPvB	22-Jan-2019	Details
Resin acids and Rosin acids, hydrogenated, esters with glycerol	266-042-9	65997-13-9	Finland	inconclusive	19-Aug-2021	Details
Resin acids and Rosin acids, hydrogenated, esters with pentaerythritol	264-848-5	64365-17-9	Finland	Under development under SEV	01-Apr-2015	Details
Resin acids and Rosin acids, sodium salts	263-144-5	61790-51-0	Finland	not PBT not vPvB	01-Apr-2015	Details
Rosin A complex combination derived from wood, especially pine wood. Composed primarily of resin acids and modified resin acids such as dimers and decarboxylated resin acids. Includes rosin stabilized by catalytic disproportionation.	232-475-7	8050-09-7	Finland	not PBT not vPvB	01-Apr-2015	Details
Rosin, hydrogenated	266-041-3	65997-06-0	Finland	not PBT not vPvB	01-Apr-2015	Details
Rosin, maleated	232-480-4	8050-28-0	Finland	not PBT not vPvB	01-Apr-2015	Details
Terphenyl	247-477-3	26140-60-3	Finland	vPvB	15-Feb-2021	Details
Terphenyl, hydrogenated	262-967-7	61788-32-7	Finland	vPvB	09-Nov-2017	Details
1,1'-(methylenedi-4,1-phenylene)bis(3-butylurea)	416-600-4	-	France	Under development	01-Apr-2015	Details
1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylindeno[5,6-c]pyran	214-946-9	1222-05-5	France	Under development under SEV	30-Jun-2022	Details
1,4,5,6,7,7-hexachloro-8,9,10-trinorborn-5-ene-2,3-dicarboxylic anhydride	204-077-3	115-27-5	France	not PBT not vPvB	23-Jun-2022	Details
2,4,6-triallyloxy-1,3,5-triazine	202-936-7	101-37-1	France	Under development	01-Apr-2015	Details
2-octyldodecan-1-ol	226-242-9	5333-42-6	France	not PBT not vPvB	01-Apr-2015	Details
3,3'-dimethylbiphenyl-4,4'-diyl diisocyanate	202-112-7	91-97-4	France	not PBT	28-Oct-2021	Details
6,6'-di-tert-butyl-4,4'-butylidenedi-m-cresol	201-618-5	85-60-9	France	Under development under SEV	02-Jun-2020	Details
Bis(dibutyldithiocarbamato-S,S')copper	237-695-7	13927-71-4	France	Under development under SEV	02-Jun-2020	Details
Dimantine	204-694-8	124-28-7	France	not PBT not vPvB	13-Sep-2017	Details
N-butyltin trichloride	214-263-6	1118-46-3	France	Under development under SEV	10-Mar-2021	Details
Octocrilene	228-250-8	6197-30-4	France	Under development under SEV	01-Apr-2015	Details
Phenol, dodecyl-, sulfurized, calcium salts	272-486-4	68855-45-8	France	inconclusive	22-Jun-2022	Details
reaction mass of 1-(1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethyl-2-naphthyl)ethan-1-one and 1-(1,2,3,4,6,7,8,8a-octahydro-2,3,8,8-tetramethyl-2-naphthyl)ethan-1-one and 1-(1,2,3,5,6,7,8,8a-octahydro-2,3,8,8-tetramethyl-2-naphthyl)ethan-1-one	915-730-3	-	France	Under development under SEV	05-Jan-2018	Details
Reaction mass of 3-[(diphenoxyphosphoryl)oxy]phenyl triphenyl 1,3-phenylene bis(phosphate) and tetraphenyl 1,3-phenylene bis(phosphate)	701-337-2	-	France	not PBT not vPvB	26-Jul-2022	Details
Reaction mass of p-t-butylphenyldiphenyl phosphate and bis(p-t-butylphenyl) phenyl phosphate	939-505-4	-	France	Under development under SEV	24-Jul-2023	Details
Reaction product of ammonium molybdate and C12-C24-diethoxylated alkylamine (1:5-1:3) ADDITIV 104	412-780-3	1380226-46-9	France	inconclusive	13-Nov-2020	Details
Reaction products of diphenylamine with nonene, branched	701-385-4	-	France	Under development under SEV	07-May-2021	Details
tert-butyl methyl ether	216-653-1	1634-04-4	France	Under development	30-Sep-2021	Details
tris(4-nonylphenyl, branched) phosphite	701-028-2	-	France	Under development under SEV	01-Apr-2015	Details
1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromo-2-methylpropoxy)benzene]	306-832-3	97416-84-7	Germany	not PBT not vPvB	20-Dec-2021	Details
1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromopropoxy)benzene]	244-617-5	21850-44-2	Germany	not PBT not vPvB	20-Dec-2021	Details
1,1,1,2,3,3-hexafluoro-2-[1,1,2,3,3,3-hexafluoro-2-[1,1,2,3,3,3-hexafluoro-2-[1,1,2,3,3,3-hexafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propoxy]propoxy]propoxy]-3-(1,2,2,2-tetrafluoroethoxy)propane	-	37486-69-4	Germany	inconclusive	03-Aug-2021	Details
1,4-Benzenediamine, N,N'-mixed Ph and tolyl and xylyl derivs.	273-226-2	68953-83-3	Germany	Under development	01-Apr-2015	Details
1,4-Benzenediamine, N,N'-mixed Ph and tolyl derivs.	273-227-8	68953-84-4	Germany	inconclusive	24-Nov-2022	Details
1,4-Benzenediamine, N,N'-mixed tolyl and xylyl derivs.	270-820-3	68478-45-5	Germany	Under development	01-Apr-2015	Details
1,4-dioxane	204-661-8	123-91-1	Germany		21-Feb-2024	Details
1-(4-methyl-2-nitrophenylazo)-2-naphthol	219-372-2	2425-85-6	Germany	inconclusive	13-Nov-2020	Details
1-[(2,4-dinitrophenyl)azo]-2-naphthol	222-429-4	3468-63-1	Germany	inconclusive	13-Nov-2020	Details
1-[(2-chloro-4-nitrophenyl)azo]-2-naphthol	220-562-2	2814-77-9	Germany	inconclusive	13-Nov-2020	Details
1-[4-(1,1-dimethylethyl)phenyl]-3-(4-methoxyphenyl)propane-1,3-dione	274-581-6	70356-09-1	Germany	Under development under SEV	01-Apr-2015	Details
2,2',6,6'-Tetrabromo-4,4'-isopropylidenediphenol, oligomeric reaction products with Propylene oxide and n-butyl glycidyl ether	926-564-6	-	Germany	not PBT	20-Feb-2023	Details
2,4-di-tert-butyl-6-(5-chlorobenzotriazol-2-yl)phenol	223-383-8	3864-99-1	Germany	vPvB	27-Mar-2019	Details
2-(1-(3',3'-dimethyl-1'-cyclohexyl)ethoxy)-2-methyl propyl propanoate HELVETOLIDE	415-490-5	141773-73-1	Germany	not PBT not vPvB	20-Dec-2021	Details
2-(2-(3-Butoxypropyl)-1,1-dioxo-1,2,4-benzothiadiazin-3-yl)-5'-tert-butyl-2-(5,5-dimethyl-2,4-dioxo-1,3-oxazolidin-3-yl)-2'-((2-ethylhexyl)thio)acetanilide	448-060-0	727678-39-9	Germany	Under development	27-Jan-2022	Details
2-(2H-benzotriazol-2-yl)-4,6-bis(1-methyl-1-phenylethyl)phenol	274-570-6	70321-86-7	Germany	Under development	01-Apr-2015	Details

Showing 1 - 100 of 236 results.

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