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Diss Factsheets
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EC number: 940-373-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
ADSORPTION/DESORPTION
The registration substance consists of very different structural elements. One is the fatty acid with a C18 carbon chain most likely responsible for a classical sorption behavior (unspecific van der Waals interaction). The other structural element is the Glucamine with 5 Hydroxyl groups responsible for the hydrogen donor properties related to the interaction with acceptors e.g. negatively charged surfaces. The sorption behavior of Glucose is well studied (e.g. Olsson et al, 2010(http://dx.doi.org/10.1016/j.jcis.2010.09.023), Kuhn et al, 2012http://dx.doi.org/10.1016/j.lwt.2012.02.010)) demonstrating that adsorption is influenced by many parameter making it difficult to predict. But not only H Donor interaction takes places with charged surfaces but also with activated, moistured carbon (Yu Sen, 2013(http://hdl.handle.net/2069/2124)). Also trapping in porous media like zeolite is possible (Kuhn et al (2010). Therefore, it is not astonishing that the sorption behavior of the test item is non-linear and a simple linear correlation to the organic carbons content of the media is not observed. In the attached EXCEL file Sheet 'Glucamide 18u Sorption data' the results on Adsorption of an Adsorption/Desorption study (see IUCLID Chapter 5.4.1) are given.
For environmental exposure calculations, the median values from soil (611 L/kg), sediment (7375 L/kg), primary sludge (173 L/kg) and activated sludge (488 L/kg) have been used.
The measured values given in the attached EXCEL file were compared with the predicted values (see EXCEL Sheet 'Property estimations') from the Property estimation programs US EPA KOC Win, (US EPA, 2011) and EUSES 2.1.2 (EU, 2015). The US EPA KOC Win uses two different models. One is a fragment based, the other is Log Kow based. The EUSES 2.1.2 model is Log Kow based. From these data it can be seen that non of the property estimation models can explain the measured data. This is another indicator that the sorption constants Kd are not only correlated to the organic carbon content but other sorption mechanism interfere.
PLEASE NOTE: Due to technical limitations the complex tables in the attached EXCEL file could not filled in directly in this text box.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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