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Diss Factsheets
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EC number: 700-857-7 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
As Rhodimet AT 88 is a transported isolated intermediaite manufactured and used under strictelly controlled conditions with a tonnage higher than 1000 tonnesper year, only acute fish, acute Daphnia magna, algae and microroganisms (Activated sludge respiration inhibition testing) toxicity data are required.
Toxicity to fish:
- In an acute aquatic toxicity study performed in accordance with OECD guideline 203 , zebra fish (Brachydanio rerio) were exposed to Rhodimet AT 88 (ALIMET) at concentrations of 0 (blank), 100, 180, 320, 580 or 1000 mg (active ingredient)/L (nominal) for 96 hours under semi-static conditions. LC50 in the test without pH adjustment at 96 hours was calculated to be 385.9 mg/L. LC50 in the test with pH adjustment at 96 hours was calculated to be 240.0 mg/L. The NOEC is 180 mg/L.
Toxicity to aquatic invertebrates:
- In an acute aquatic toxicity study performed in accordance with OECD guideline 202, Daphnia magna were exposed to Rhodimet AT 88 (ALIMET) at concentrations of 0 (blank), 58, 100, 180, 320, 580 or 1000 mg (active ingredient)/L (nominal) for 48 hours under semi-static conditions.
The LC50 and EC50 (48 hour), without pH adjustment, were determined to be 222 (195-261) and 200 (176-232) mg (a.i.)/L, respectively.
The LC50 and EC50 (48 hour), with pH adjustment, were determined to be 293 (242-361) and 287 (237-352) mg (a.i.)/L, respectively.
Toxicity to algae:
In an algal toxicity study performed in accordance with OECD guideline 201, Selenastrum capricornutum was exposed to Rhomimet AT 88 (Alimet) at concentrations of 0 (control), 10, 18, 32, 58, 100 and 180 mg (active ingredient)/L (nominal) for 72 hours under static conditions.
The ErC50 (72 hour), without pH adjustment, was determined to be 89 mg (a.i.)/L.
The ErC50 (72 hour), with pH adjustment, wasdetermined to be 130 mg (a.i.)/L.
The No-Observed-Effect-Concentration (NOEC) after 72 hours was calculated to be 58 mg (a.i.)/L.
Toxicity to microorganisms:
A study was conducted to assess the effect of Rhodimet AT 88 (ALIMET) on micro-organisms according to OECD guideline 209 . The test material was tested at concentrations of 10, 32, 100, 320 and 1000 mg/L(nominal) and the inoculum (microbial source) was activated sludge of a predominantly domestic sewage. Toxicity to micro-organisms was assessed by measuring the respiration rate.
Under the test conditions, the EC50 (3 hour) of ALIMET was considered to be > 1000 mg/L.
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