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EC number: 217-443-2 | CAS number: 1852-17-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil macroorganisms except arthropods
Administrative data
- Endpoint:
- toxicity to soil macroorganisms except arthropods: short-term
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 001
- Report date:
- 2001
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 207 (Earthworm, Acute Toxicity Tests)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2-imidazolidone
- EC Number:
- 204-436-4
- EC Name:
- 2-imidazolidone
- Cas Number:
- 120-93-4
- IUPAC Name:
- imidazolidin-2-one
- Details on test material:
- - Name of test material (as cited in study report): BF 222-EU
- IUPAC-name: Imidazolidine-2-one
- Batch No.: 27270
- Analytical purity: 88.6 %
Constituent 1
Test organisms
- Test organisms (species):
- Eisenia fetida
- Animal group:
- annelids
- Details on test organisms:
- TEST ORGANISM
- Common name: Earthworms
- Source: From in-house culture
- Age at test initiation: Adult animals with clitellum, less then one year old
- Weight at test initiation: Between 250 and 600 mg
ACCLIMATION
- Acclimation conditions: Before being used in the test, the animals were kept in boxes an fed with horse manure.
- Adaptation: About 24 hours to artificial soil
Study design
- Study type:
- laboratory study
- Substrate type:
- artificial soil
- Limit test:
- no
- Total exposure duration:
- 14 d
Test conditions
- Test temperature:
- 20 - 21 °C
- pH:
- 5.8
- Moisture:
- water contant (dry weight):
at test initiation 34.8 g/100 g soil
at test termination 32.5 g/100 g soil - Details on test conditions:
- TEST SYSTEM
- Test container: 1 L preservation jars (glass)
- Amount of soil or substrate: 750 g wet weight
- No. of organisms per container: 10
- No. of replicates per treatment group: 4
- No. of replicates per control: 4
SOURCE AND PROPERTIES OF SUBSTRATE
- Artificial soil according to OECD 207:
69 % Quarz sand (Fa. Gebr. Willersinn, Particle size 0.063 - 0.2 mm)
20 % Kaolin (BASF Kaolin B22)
10 % Sphagnum peat (Gartengold Order No. 14030, DIN 11540-F250)
1% CaCO3 (Riedel-de Häen, Order No. 12010)
OTHER TEST CONDITIONS
- Photoperiod: continuous illumination
EFFECT PARAMETERS MEASURED:
After 7 days worm mortality was assessed by emptying the glass containers onto suitable trays and estimating the survived worms. Additionally their reaction to mechanical stimulus and other anormalities were observed. After 14 days the same assessment was done and additionally the live weight of the worm was determined after gentle washing and drying. - Nominal and measured concentrations:
- Test concentrations (dry weight) nominal based on the batch (88.6 % purity): 0, 197.5, 296.3, 444.4, 666.7 and 1000 mg/kg
Test concentrations (dry weight) actual based on calculation (100 % purity): 0, 175, 262.5, 393.7, 590.7 and 886 mg/kg - Reference substance (positive control):
- yes
- Remarks:
- Chloracetamide
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 14 d
- Dose descriptor:
- LC50
- Effect conc.:
- > 886 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Duration:
- 14 d
- Dose descriptor:
- other: NOAEC
- Effect conc.:
- > 886 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: mortality and biomass
- Details on results:
- The substance caused no mortality on earthworm even in the highest concentration. Neither a reduction in worm biomass could be measured. In contrary the biomass rised in all variants especially in the treatement groups with higher test concentrations. No other particular behavioural or morphological changes were observed.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.