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EC number: 271-689-5 | CAS number: 68604-38-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The chemical safety assessment according to Annex I of Regulation (EC) No. 1907/2006 does not indicate the need to investigate further the toxicity to soil microorganisms.
Key value for chemical safety assessment
Additional information
Experimental data on the toxicity of Fatty acids, C16-18 and
C18-unsatd., hexaesters with dipentaerythritol (CAS 68604-38-6) to soil
microorganisms are not available. In accordance with Regulation (EC) No.
1907/2006, Annex IX, column 2, 9.4 studies on terrestrial organisms do
not need to be conducted when there is no risk indicated by the chemical
safety assessment.
Based on the available experimental toxicity data the substance is
expected to be not toxic to soil organisms. A study on the chronic
toxicity of the substance to Eisenia fetida according to OECD 222
determined no acute or chronic toxicity (NOEC reproduction (56 d) ≥ 1000
mg/kg soil dw). The substance is expected to be largely physically
removed in sewage treatment plants and thus a transfer to the
terrestrial environment is not likely. If transferred to the soil an
adsorption to soil particles is probable as indicated by the high log
Koc (C16 FA component: 2.27, C18 unsat. FA component: 46.87, C18 FA
component: 48.16; KOWWIN v1.68; Blum, 2011).
A toxicity control in the biodegradation study with the test substance
shows no inhibition to aquatic microorganisms resulting in a NOEC (14 d)
≥ 20 mg/L (based on test material). The applied test concentration is in
the range of concentrations that can be expected in the influent of a
sewage treatment plant, as the substance is characterised by poor water
solubility (< 0.15 mg/L). The ECHA Guidance Document R.7c (ECHA, 2012)
states that a test on soil microbial activity will only be additionally
necessary for a valid PNEC derivation if inhibition of sewage sludge
microbial activity has occurred.
In the absence of a clear indication of selective toxicity, an
invertebrate (earthworm or collembolan) test is preferred, as outlined
in ECHA Guidance Document R.7c, section R.7.11.5.3 (ECHA, 2012). A study
on the chronic toxicity of the substance to earthworms determined no
acute or chronic toxicity (see above).
In addition, the long-term toxicity of the substance to Daphnia magna
was tested in a guideline study following OECD 211 (Caduff, 2013). An
effect on survival or reproduction rate of Daphnia was not observed
within the limit of water solubility (NOEC (21 d) ≥ 100 mg/L).
When ingested by aquatic organisms, a relevant uptake is not expected
for the substance since it will be presumably metabolised and excreted.
Bioaccumulation is therefore not anticipated.
In conclusion, the substance is unlikely to pose a risk for terrestrial
microorganisms based on a) the lack of exposure and b) the low toxicity
as expected for this substance for the terrestrial compartment based on
the available experimental data, metabolism considerations and the lack
of adverse effects in aquatic ecotoxicity tests.
In accordance with Regulation (EC) No. 1907/2006, Annex X, Column 2, 9.4
further studies on the effects on terrestrial organisms do not have to
be conducted since the chemical safety assessment indicates that
toxicity to soil microorganisms is not expected to be of concern.
A detailed reference list is provided in the technical dossier
(see IUCLID, section 13) and within CSR.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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