N-glycylglycine

Vapour pressure

Administrative data

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

25 June - 23 October 2020

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2020

Report date:

2020

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7950 (Vapor Pressure)

Version / remarks:

1996

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Version / remarks:

(EC) No. 440/2008

Deviations:

no

Test guideline 3

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Version / remarks:

2006

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

effusion method: Knudsen cell

Test material

Test material information

Constituent 1

Reference substance name:

N-glycylglycine

EC Number:

209-127-8

EC Name:

N-glycylglycine

Cas Number:

556-50-3

Molecular formula:

C4H8N2O3

IUPAC Name:

N-glycylglycine

Test material form:

solid: crystalline

Details on test material:

Batch Number: S119 0711
Storage conditions: room temperature

Specific details on test material used for the study:

Batch No.: S119 0711
Storage: At room temperature (approx. 15-25°C), dry

Results and discussion

Vapour pressure

Vapour pressure 1

Key result

Temp.:

50 °C

Vapour pressure:

< 0.058 Pa

Remarks on result:

other: estimated on the basis of the maximum measured vapour pressures

Vapour pressure 2

Key result

Temp.:

25 °C

Vapour pressure:

< 0.058 Pa

Remarks on result:

other: estimated on the basis of the maximum measured vapour pressures

Vapour pressure 3

Key result

Temp.:

20 °C

Vapour pressure:

< 0.058 Pa

Remarks on result:

other: estimated on the basis of the maximum measured vapour pressures

Any other information on results incl. tables

The vapour pressure was measured in the temperature range of 40 to 150°C. The measured vapour pressure values together with the measured temperatures are shown in the table in the next section "overall remarks".

Due to the fact that the test item showed no proper linear correlation of the vapour pressure and the inverse temperature 1/T, the Antoine constants cannot be evaluated in the measured temperature range. Therefore, the vapour pressure will be estimated according to the measured vapour pressures.

The test item Glycyl-glycine showed no evaluable vapour pressure curve in the temperature range of 40 to 150°C. Due to this result, the vapour pressures for the temperatures 20, 25 and 50°C are estimated on the basis of the maximum measured vapour pressures, according to Regulation (EC) No. 440/2008 Method A.4.and OECD Test Guideline 104 (2006).

Temperature / °C	Vapour pressure / Pa
20	<5.8E-2
25	<5.8E-2
50	<5.8E-2

Applicant's summary and conclusion

Conclusions:

The test item Glycyl glycine (CAS no. 556-50-3) showed no evaluable vapour pressure curve in the temperature range of 40 to 150°C. Due to this result, the vapour pressures for the temperatures 20, 25 and 50°C are estimated on the basis of the maximum measured vapour pressures, according to Regulation (EC) No. 440/2008 Method A.4. and OECD Test Guideline 104 (2006). The vapour pressure of the test item was <5.8 × 10-2 Pa at 20°C, 25°C and 50°C.

Executive summary:

The test item Glycyl glycine (CAS no. 556-50-3) showed no evaluable vapour pressure curve in the temperature range of 40 to 150°C. Due to this result, the vapour pressures for the temperatures 20, 25 and 50°C are estimated on the basis of the maximum measured vapour pressures, according to Regulation (EC) No. 440/2008 Method A.4. and OECD Test Guideline 104 (2006). The vapour pressure of the test item was <5.8 × 10-2 Pa at 20°C, 25°C and 50°C.