Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 276-123-0 | CAS number: 71873-46-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From April 06th to September 27th, 1989
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Version / remarks:
- part I, adopted 1984
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.2 (Acute Toxicity for Daphnia)
- Version / remarks:
- September 19, 1984
- GLP compliance:
- no
- Analytical monitoring:
- no
- Vehicle:
- no
- Details on test solutions:
- Test item was dissolved in the test medium at a concentration of 100 mg/100 ml (stock solution). Thereafter, series of sequential dilutions with the test medium were prepared to obtain the final test concentrations of the test article.
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Animals were bred in the testing laboratory, under standardized conditions.
for the test, animals with an age of less than 24 hours were used. - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 24 h
- Test temperature:
- 21.5 °C
- pH:
- Start: 8.4
End: 8.3 - Dissolved oxygen:
- Start: 8.6 mg/l
End: 9.0 mg/l - Nominal and measured concentrations:
- Nominal 0, 1, 10 and 100 mg/l
- Details on test conditions:
- TEST SYSTEM
- Test vessel: 50 ml beakers.
- Volume: beakers contain 20 ml of test medium.
- No. of organisms per vessel: 10 animals.
- No. of vessels per concentration: 2 replicates.
- No. of vessels per control: 2 replicates.
TEST MEDIUM / WATER PARAMETERS
- Preparation of dilution water: bidistilled water.
- Test medium: according to the Directive EEC.
- CaCl2 x 2H2O: 294 mg/l
- MgSO4 x 7H2O: 123 mg/l
- NaHCO3: 65 mg/l
- KCl: 5.8 mg/l.
OTHER TEST CONDITIONS
- Adjustment of pH:pH of reconstituted water was adjusted to 7.9 ± 0.3.
- Photoperiod: 16 hours of illumination.
- Light intensity: 1000 Lux.
EFFECT PARAMETERS MEASURED
Test evaluations were done according to the Guideline No. 202 of the OECD by visual control of the mobility of the daphnids after 24 hours. Based on the data, an estimate of the EC0, 50 and 100 was given. - Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- No deaths occurred over the exposure period of 24 hours. EC0 (24h): 100 mg/l
Appearance of the test medium: blue solution. - Conclusions:
- EC50 (24h) > 100 mg/l (nominal)
- Executive summary:
The acute toxicity of the test substance to Daphnia magna was investigated over a period of 24 hours, following the OECD guideline 202, part I (1984). The nominal test concentrations applied were 0, 1, 10 and 100 mg/l; all tests were run in duplicate. No chemical analysis of the test substance concentration was conducted. No deaths occurred at the nominal concentration of 100 mg/l; 10 % of mortality was observed in one of the two blank controls. The EC0 was identified to be 100 mg/l. Test medium appeared to be blue solution.
Conclusion
EC50 (24h) > 100 mg/l (nominal)
Reference
Influence of test item on the immobilization of Daphnia magna, after 24 hours of exposure
Concentration (mg/l) | N. of daphnids | N. of responses | % of responses |
Control | 10 | 1 | 10 |
Control | 10 | 0 | 0 |
Test item 1 | 10 | 0 | 0 |
Test item 1 | 10 | 0 | 0 |
Test item 10 | 10 | 0 | 0 |
Test item 10 | 10 | 0 | 0 |
Test item 100 | 10 | 0 | 0 |
Test item 100 | 10 | 0 | 0 |
Description of key information
EC50 (24h) > 100 mg/l (nominal)
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 100 mg/L
Additional information
The acute toxicity of the test substance to Daphnia magna was investigated over a period of 24 hours, following the OECD guideline 202, part I (1984). No chemical analysis of the test substance concentration was conducted. No deaths occurred at the nominal concentration of 100 mg/l; 10 % of mortality was observed in one of the two blank controls. The EC0 was identified to be 100 mg/l. Test medium appeared to be blue solution.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.