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EC number: 231-545-4 | CAS number: 7631-86-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Nanomaterial Zeta potential
Administrative data
- Endpoint:
- nanomaterial Zeta potential
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 016
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Type of method:
- vibration potential
- Details on methods and data evaluation:
- The zeta potential of the test item PERKASIL® SM 660 in water was determined by measuring the Colloidal Vibration Current (CVI) of a pre-treated dispersion of the test material.
The pre-treatment of the test item includes the production of a 10 wt.-% dispersion with a lab stirrer, ultra-sonication and centrifugation to get standardized condition for the CVI measurement.
The needed parameter particle size distribution of dispersion and density of raw material were measured by laser diffraction and He-Density method.
The measurement of CVI is conducted under constant stirring with a magnetic lab stirrer at 300rpm.
70mL of the sample are poured in the vessel of the CVI instrument. Additionally to the measurement of CVI, pH, conductivity and temperature should be monitored to determine the zeta potential as accurate as possible. If the pH value is below 6.5, it is standardized to this value by titration of NaOH solution.
The result for zeta potential is displayed with the unit millivolt (mV).
Deviation from the Study plan:
As the sponsor ordered additionally, the analysis of zeta potential as function of pH value was conducted by two titrations:
One completely prepared dispersion (see 5.1.2) was titrated with NaOH 1M solution and a second dispersion was titrated with HCl 1M solution. These two titrations had been merged to receive an overview about the whole pH range. To control the ionic strength in dispersion, aqueous conductivity was monitored continuously.
Test material
- Reference substance name:
- Silicon dioxide
- EC Number:
- 231-545-4
- EC Name:
- Silicon dioxide
- Cas Number:
- 7631-86-9
- Molecular formula:
- O2Si
- IUPAC Name:
- dioxosilane
- Test material form:
- solid: nanoform, no surface treatment
- Details on test material:
- Precipitated, Surface area / BET [m2/g]: 182
Constituent 1
- Specific details on test material used for the study:
- Designation in Test Facility: PERKASIL® S 660
Date of Receipt: 15. June 2016
Condition at receipt: closed vessel, in proper conditions
Name: PERKASIL® KS 408 PD
Code No.: 1601257005
Appearance: White Powder
Composition: SiO2, synthetic amorphous
CAS No.: 7631-86-9
EINECS No.: 231-545-4
Molecular Formula: SiO2
Molecular Weight: 60,2
Purity: 95-100% SiO2
Homogeneity: homogeneous material
Production Date: not stated
Expiry Date: 2018
Storage: Room Temperature: (20 ± 5°C)
Hazard information: none
H-phrases: none
P-phrases: none
Reference material / nanomaterial and sample identification number
Reference
- Reference substance name:
- Unnamed
Data gathering
- Instruments:
- 4.3 Analytical Instrument Laser Diffraction
4.3.1 CILAS 1190L
Specification: 1190L
Serial number: 3508
Software: Particle Expert V9.40
Date of Purchase: Feb. 2010
Producer: CILAS, Orleans, France
Usage and calibration following the corresponding AA-007 in the current version.
4.3.2 Method Parameters Laser Diffraction
• Measurement time: 60 seconds
• Ultrasonic: 60 seconds before measurement at 50W
• Pump speed: 320 rpm
• Stirrer speed: 120 rpm
• Data treatment: Fraunhofer theory
4.4 Analytical Instrument Helium Pycnometry:
Specification: Ultra Pyc 1200e
Serial number: 1221305080/1
Software: V5.03
Date of Purchase: Apr. 2010
Producer: Quantachrome Instruments, Florida, USA
Usage and calibration following the corresponding AA-009 in the current version.
4.5 Analytical Instrument Electroacoustic Spectrometry
Specification: DT 1202
Serial number: 562
Software: 5.6.37
Date of Purchase: Sep. 2014
Producer: Dispersion Technology, New York, USA
Usage and calibration following the corresponding AA-008 in the current version.
4.6 Instrument and Devices
The following instruments and devices were used in the performance of the study:
• Analytical Scales, OHAUS ARC 120
• Sonotrode, Bandelin
• Centrifuge, ThermoFisher Scientific
• Moisture Analyzer, Sartorius
• Lab Stirrer Eurostar, IKA
• pH-meter, Horiba
• Conductivity meter, Dispersion Technology
• Thermometer, Dispersion Technology
Usage and, if applicable, calibration of all instruments following the corresponding AA in the
current edition. - Reproducibility:
- The results show good reproducibility and are in the expected range for these materials.
Results and discussion
Zeta potential
- Key result
- Zeta potential:
- -40.23 mV
- St. dev.:
- 0.236 mV
- pH:
- 6.8
- Medium:
- Distilled Water with a conductivity below 10 μS/cm is used for production of the dispersion.
Applicant's summary and conclusion
- Conclusions:
- The CVI measurement was repeated two times with the following result:
Colloidal Vibration Current:
Mean Value [mV(s/g)1/2]: 1247612; Std. Deviation[mV(s/g)1/2]: 7053
Calculated Zeta Potential:
Mean Value [mV]: -40.23; Std. Deviation [mV]: 0.236 - Executive summary:
The zeta potential of the test item PERKASIL® SM 660 in water was determined by measuring the Colloidal Vibration Current (CVI) of a pre-treated dispersion of the test material.
The pre-treatment of the test item includes the production of a 10 wt.-% dispersion with a lab stirrer, ultra-sonication and centrifugation to get standardized condition for the CVI measurement.
The needed parameter particle size distribution of dispersion and density of raw material were measured by laser diffraction and He-Density method.
The CVI measurement was repeated two times with the following results:
Colloidal Vibration Current:
Mean Value [mV(s/g)1/2]: 1247612; Std. Deviation[mV(s/g)1/2]: 7053
Calculated Zeta Potential:
Mean Value [mV]: -40.23; Std. Deviation [mV]: 0.236
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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