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EC number: 800-038-5 | CAS number: 1071838-81-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Translation of a japanese report (2012-06-01) GLP certificate not translated in the report
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
- Deviations:
- no
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: mixture of non-adapted sludge
- Details on inoculum:
- - Source of inoculum/activated sludge: Sludge sampling was carried out at 10 locations in Japan (samples were from surface water and surface soil of rivers, lakes, and inland sea; or return sludges from sewage plants)
- Storage length: Not defined exactly
- Sampling period: December 2010; initiation date of use: January 5, 2011.
- Pretreatment: the activated sludge was cultivated for 19 hours after the synthetic sewage was added before its used
- Concentration of sludge: 3400 mg/L of suspended solid (February 7, 2011)
- Initial cell/biomass concentration: Not avalaible
2.65 mL was added to each test vessel concerned, so that the concentration of the suspended solid reached 30 mg/L.
- Duration of test (contact time):
- ca. 0 - ca. 28 d
- Initial conc.:
- ca. 100 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Parameter followed for biodegradation estimation:
- DOC removal
- Parameter followed for biodegradation estimation:
- test mat. analysis
- Remarks:
- Detection of N-guanylurea; nitric acid ion, water-soluble copper and water-insoluble copper
- Details on study design:
- TEST CONDITIONS
- Composition of medium: basal culture medium (3 mL of each solution A, B, C and D (described in JIS K 0102-2010 section 21) and make up to 1 L with purified water
- Additional substrate: None
- Solubilising agent (type and concentration if used): None
- Test temperature: 25 +/- 1°C
- pH: 7.0 (basal culture medium)
- pH adjusted (basal culture medium): yes
- Aeration of dilution water: No information in the report
- Suspended solids concentration: 30 mg/L
- Continuous darkness: yes
- Other: each test soution was stirred by a stirrer
- Test vessel: volume 300 mL
TEST SYSTEM
- Culturing apparatus: closed system oxygen consumption measuring apparatus
- Number of culture flasks/concentration:
- Test solution to 100 mg/L (water + test item): 1 vessel
- Test solution to 100 mg/L (sludge + test item): 3 vessels
- Test solution to 100 mg/L (sludge + aniline): 1 vessel
- Control blank: 1 vessel
- Abiotic sterile control: None
- Toxicity control: None
- Method used to create aerobic conditions: Not available
- Measuring equipment: temperature controlled bath (containing a measuring unit) AI-0001 (Asahi Techneion Co., Ltd.); Data sampler OM7000A (Ohkura Electric Co., Ltd.)
- Details of trap for CO2 if used: soda lime No.1 (Wako Pure Chemical Industries, Ltd.)
SAMPLING
- Sampling frequency: continuous measurement (BOD) by a closed system oxygen consumption measuring apparatus
- Sampling method: /
- Sample storage before analysis: /
- Other: /
STATISTICAL METHODS: None - Reference substance:
- aniline
- Remarks:
- 100 mg/L (CAS number: 62-53-3; supplier: Wako Pure Chemical Industries Ltd., lot number: EPL1617)
- Preliminary study:
- A preliminary test showed that the test item was hydrolyzed rapidly in water.
Hydrolysis study of test item:
Results of the percentage detection of N-guanylurea (purified water + test item (100 mg/L of CuGun)):
0 hour: 1% of N-guanylurea
0.5 hour: 57.5% of N-guanylurea
1 hour: 100.5% of N-guanylurea
2 hours: 101% of N-guanylurea
3 hours: 100.5% of N-guanylurea - Parameter:
- % degradation (O2 consumption)
- Remarks:
- with a closed system oxygen consumption measuring apparatus
- Value:
- 0
- Sampling time:
- 28 d
- Remarks on result:
- other: continuous measurements
- Parameter:
- % degradation (DOC removal)
- Value:
- < 5
- Sampling time:
- 28 d
- Remarks on result:
- other: Average percentage detection: 96%
- Details on results:
- Average percentage biodegradation by BOD after 28 d: 0% ( average percentage of degradation:- 5%. The value of control blank was subtracted from the values of the test solutions (sludge + test item)).
Average percentage detection of DOC after 28 d: 96%
Average percentage detection of N-guanylurea after 28 d: 97%
Average percentage detection of nitric acid ion after 28 d: 97%
Average percentage detection of water-soluble copper after 28 d: 0%
Average percentage detection of water-insoluble copper after 28 d: 105% - Results with reference substance:
- % biodegradation BOD 28 d: 76% (7 d: 62%)
% biodegradation DOC 28 d: Not available - Validity criteria fulfilled:
- yes
- Remarks:
- Difference between extremes of replicate values of % biodegradation (by BOD): 1% (< 20%); % biodegradation of aniline by BOD: after 7 days 62% (>= 40%) and after 14 days 75% (>= 65%); BOD value of control blank (after 28 days): 7.1 mg (< 60 mg/L)
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- Report conclusion:
Under the test conditions of this study, the test item: Copper Guanylurea nitrate, a salt formed from copper-N-guanylurea complex ion (cationic component) and nitric acid ion (anionic component) is rapidly hydrolyzed in water (transformation products: N-guanylurea, nitric acid ion and copper).
Copper in the test item was remained as a water-insoluble and inorganic form in the test solution .
Nitric acid ion contained as an anionic component in the test item was remained as a dissociated form in the test solution and although N-guanylurea, which is an organic component, was freed in the test solution, it was not biodegraded in this study.
Reference
Calculation table for percentage biodegradation by BOD (CuGun: 100 mg/L; duration of cultivation: 28 days)
Vessels | 7th day | 14th day | 21st day | 28th day | Mean | ||||
BOD (mg) | Deg. (%) | BOD (mg) | Deg. (%) | BOD (mg) | Deg. (%) | BOD (mg) | Deg. (%) | Deg. (%) | |
Sludge + aniline | 57.9 | 62 | 71.9 | 75 | 75.7 | 76 | 75.7 | 76 | - |
Control blank | 2.0 | - | 4.4 | - | 7.1 | - | 7.1 | - | - |
Sludge + test item | 1.6 | -1 | 3.2 | -4 | 5.4 | -5 | 5.4 | -5 | -5 |
Sludge + test item | 1.5 | -1 | 3.2 | -4 | 5.4 | -5 | 5.4 | -5 | |
Sludge + test item | 1.7 | -1 | 3.5 | -3 | 5.7 | -4 | 5.7 | -4 | |
Water + test item | 0.0 | - | 0.1 | - | 1.2 | - | 1.2 | - | - |
Description of key information
Under the test conditions of this study, the test item: Copper Guanylurea nitrate, a salt formed from copper-N-guanylurea complex ion (cationic component) and nitric acid ion (anionic component) is rapidly hydrolyzed in water (transformation products: N-guanylurea, nitric acid ion and copper).
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
Copper in the test item was remained as a water-insoluble and inorganic form in the test solution . Nitric acid ion contained as an anionic component in the test item was remained as a dissociated form in the test solution and although N-guanylurea, which is an organic component, was freed in the test solution, it was not biodegraded in this study.
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