Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1.3.-1.5.1976
Reliability:
3 (not reliable)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1976
Report date:
1976

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 405 (Acute Eye Irritation / Corrosion)
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
Methyl (3-hydroxyphenyl)-carbamate
EC Number:
237-196-4
EC Name:
Methyl (3-hydroxyphenyl)-carbamate
Cas Number:
13683-89-1
IUPAC Name:
methyl (3-hydroxyphenyl)carbamate
Constituent 2
Reference substance name:
methyl-N-(3-hydroxyphenyl)-carbamate
IUPAC Name:
methyl-N-(3-hydroxyphenyl)-carbamate

Test animals / tissue source

Species:
rabbit
Strain:
other: albino

Test system

Vehicle:
not specified
Controls:
not specified
Amount / concentration applied:
0.1 g
Number of animals or in vitro replicates:
no data

Results and discussion

In vivo

Results
Irritation parameter:
overall irritation score
Basis:
mean
Time point:
other: 24 h
Score:
8
Reversibility:
fully reversible
Irritant / corrosive response data:
congestion

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
The substance is not classified according to CLP and DSD.