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EC number: 234-858-4 | CAS number: 12037-47-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (48h) > 100 mg/L (OECD 202), RA
Key value for chemical safety assessment
Additional information
Since no studies investigating the short-term toxicity to aquatic invertebrates of Silicon orthophosphate (CAS No. 12037-47-7) are available for this endpoint, in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 Grouping of substances and read-across, a read-across was conducted based on the products of dissociation. The read across is explained within the read across justification in section 13.
Silicon orthophosphate (CAS No. 12037-47-7) is readily soluble in water, dissociating into silicon and phosphate ions. Consequently, the chemical assessment is based on the products of dissociation. The substances which were chosen for the read across approach yield the same ions as the target substance (either ionic silicon or ionic orthophosphate) when dissolved in water. Data from phosphoric acid, potassium salt (2:3), dihydrate (CAS No. 6922-99-4) are used to cover the short-term toxicity to aquatic invertebrates of the phosphate moiety of the substance. Data from silicon dioxide (CAS No. 7631 -86 -9) are used to cover the silicon moiety of the substance.
Phosphoric acid, potassium salt (2:3), dehydrate (CAS No. 6922-99-4), was tested in a 48 h limit test according to OECD 202 under GLP conditions, including analytics (Priestly and Mullee, 2010). At a nominal test concentration of 100 mg/L, no mortality occurred in the control and test groups. Therefore, an EC50 (48h) > 100 mg/L was assumed.
Silicon dioxide (CAS No. 7631 -86 -9) was tested in a 24 h GLP-study without analytical verification of the test substance concentrations (Hooftman and van Drongelen-Sevenhuijsen, 1992). Test suspensions at nominal 1,000 and 10,000 mg/L were used after settling. As no immobilisation or adverse effects occurred in the control and test groups, an EL50 (24h) > 10,000 mg/L (nominal) was assumed.
Therefore, based on the read across approach an EC50 (48h) > 100 mg/L can be assumed for silicon orthophosphate.
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