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Diss Factsheets
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EC number: 200-927-2 | CAS number: 76-03-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_environmental-fate-and-pathways.png)
Field studies
Administrative data
- Endpoint:
- field studies
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Well documented method. No data on GLP.
Data source
Reference
- Reference Type:
- publication
- Title:
- Long-Term Exposure of Sitka Spruce Seedlings to Trichloroacetic Acid
- Author:
- Cape JN, Reeves NM, Schröder P, Heal R
- Year:
- 2 003
- Bibliographic source:
- Environ. Sci. Technol. 2003, 37, 2953-2957
Materials and methods
- Principles of method if other than guideline:
- This experiment reports the results from treating 4-year-old Sitka spruce (Picea sitchensis (Bong.) Carr) plants in a greenhouse over a growing season with Trichloroacetic acid supplied either to the soil or to the foliage at concentrations of 10 and 100 ng/mL. Chemical analysis used automated headspace gas chromatography (Perkin-Elmer HS40XL) with electron capture detection following thermal decarboxylation of TCA to give CHCl3.
- GLP compliance:
- not specified
- Type of measurement:
- Chemical analysis used automated headspace gas chromatography (Perkin-Elmer HS40XL) with electron capture detection following thermal decarboxylation of TCA to give CHCl3.
- Media:
- This experiment reports the results from treating 4-year-old Sitka spruce (Picea sitchensis (Bong.) Carr) plants in a greenhouse over a growing season with Trichloroacetic acid supplied either to the soil or to the foliage at concentrations of 10 and 100 ng/mL.
Test material
- Reference substance name:
- Trichloroacetic acid
- EC Number:
- 200-927-2
- EC Name:
- Trichloroacetic acid
- Cas Number:
- 76-03-9
- Molecular formula:
- C2HCl3O2
- IUPAC Name:
- trichloroacetic acid
- Details on test material:
- - Name of test material (as cited in study report): Trichloroacetic acid, TCA
Constituent 1
Results and discussion
Any other information on results incl. tables
Similar uptake of Trichloroacetic acid by needles was observed for both modes of treatment, with significant accumulation of Trichloroacetic acid (300 ng/g dry wt) at the higher concentration. Larger concentrations in stem tissue were seen for the foliar-applied Trichloroacetic acid (280 ng/g) than for the soil-applied Trichloroacetic acid (70 ng/g), suggesting that direct stem uptake may be important. Six months after treatments stopped, Trichloroacetic acid concentrations in the needles of plants exposed to 100 ng/mL Trichloroacetic acid were still enhanced, showing that biological degradation of Trichloroacetic acid in needles was slow over the winter. By contrast, no significant enhancement of Trichloroacetic acid in soil could be detected in the directly treated soils even during the experiment. The protein content of needles treated with the higher concentration of Trichloroacetic acid either route was significantly smaller than for the controls, but there was no effect of Trichloroacetic acid on the conjugation of 1-chloro-2,4-dinitrobenzene in roots nor on the conjugation of 1,2-dichloro-4-nitrobenzene in needles.
Applicant's summary and conclusion
- Conclusions:
- Similar uptake of Trichloroacetic acid by needles was observed for both modes of treatment, with significant accumulation of Trichloroacetic acid (300 ng/g dry wt) at the higher concentration. Larger concentrations in stem tissue were seen for the foliar-applied Trichloroacetic acid (280 ng/g) than for the soil-applied Trichloroacetic acid (70 ng/g), suggesting that direct stem uptake may be important. Six months after treatments stopped, Trichloroacetic acid concentrations in the needles of plants exposed to 100 ng/mL Trichloroacetic acid were still enhanced, showing that biological degradation of Trichloroacetic acid in needles was slow over the winter. By contrast, no significant enhancement of Trichloroacetic acid in soil could be detected in the directly treated soils even during the experiment. The protein content of needles treated with the higher concentration of Trichloroacetic acid either route was significantly smaller than for the controls, but there was no effect of Trichloroacetic acid on the conjugation of 1-chloro-2,4-dinitrobenzene in roots nor on the conjugation of 1,2-dichloro-4-nitrobenzene in needles.
- Executive summary:
Trichloroacetic acid has been implicated as an airborne pollutant responsible for adverse effects on forest health. There is considerable debate as to whether Trichloroacetic acid observed in trees and forest soils is derived from atmospheric deposition or from in situ production.
This experiment reports the results from treating 4-year-old Sitka spruce (Picea sitchensis (Bong.) Carr) plants in a greenhouse over a growing season with Trichloroacetic acid supplied either to the soil or to the foliage at concentrations of 10 and 100 ng/mL. Chemical analysis used automated headspace gas chromatography (Perkin-Elmer HS40XL) with electron capture detection following thermal decarboxylation of TCA to give CHCl3.
Similar uptake of Trichloroacetic acid by needles was observed for both modes of treatment, with significant accumulation of Trichloroacetic acid (300 ng/g dry wt) at the higher concentration. Larger concentrations in stem tissue were seen for the foliar-applied Trichloroacetic acid (280 ng/g) than for the soil-applied Trichloroacetic acid (70 ng/g), suggesting that direct stem uptake may be important. Six months after treatments stopped, Trichloroacetic acid concentrations in the needles of plants exposed to 100 ng/mL Trichloroacetic acid were still enhanced, showing that biological degradation of Trichloroacetic acid in needles was slow over the winter. By contrast, no significant enhancement of Trichloroacetic acid in soil could be detected in the directly treated soils even during the experiment. The protein content of needles treated with the higher concentration of Trichloroacetic acid either route was significantly smaller than for the controls, but there was no effect of Trichloroacetic acid on the conjugation of 1-chloro-2,4-dinitrobenzene in roots nor on the conjugation of 1,2-dichloro-4-nitrobenzene in needles.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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