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EC number: 226-002-3 | CAS number: 5205-93-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Distribution modelling
Administrative data
- Endpoint:
- distribution modelling
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- estimated by calculation
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 009
Materials and methods
- Model:
- calculation according to Mackay, Level III
- Calculation programme:
- A Mackay level III distribution was calculated using EPIwin v. 3.20
- Release year:
- 2 007
- Media:
- air - biota - sediment(s) - soil - water
Test material
- Reference substance name:
- N-[3-(dimethylamino)propyl]methacrylamide
- EC Number:
- 226-002-3
- EC Name:
- N-[3-(dimethylamino)propyl]methacrylamide
- Cas Number:
- 5205-93-6
- Molecular formula:
- C9H18N2O
- IUPAC Name:
- N-[3-(dimethylamino)propyl]-2-methylacrylamide
- Test material form:
- liquid
Constituent 1
Study design
- Test substance input data:
- Distributions were calculated with the following factors:
Level III Fugacity Model (Full-Output):
=======================================
Chem Name : 2-Propenamide, N- 3-(dimethylamino)propyl -2-methyl-
Molecular Wt: 170.26
Henry's LC : 6.72e-010 atm-m3/mole (calc VP/Wsol)
Vapor Press : 0.003 mm Hg (user-entered)
Log Kow : 0.5 (user-entered)
Soil Koc : 1.3 (calc by model)
Results and discussion
Percent distribution in media
- Air (%):
- 0
- Water (%):
- 99.8
- Soil (%):
- 0
- Sediment (%):
- 0.198
- Other distribution results:
- According to the model calculation, emissions into water basically stay there while emissions into air are partly removed by photodegradation while other parts partition to the soil and water compartments. It should be noted that the model substantially over-estimates the persistence time in water and soil. In reality the substance is readily biodegradable and the persistence times are lower.
Any other information on results incl. tables
Level III Fugacity Model (Full-Output) - Emission into Water (for Emission into Air see below)
=======================================
Chem Name : 2-Propenamide, N- 3-(dimethylamino)propyl -2-methyl-
Molecular Wt: 170.26
Henry's LC : 6.72e-010 atm-m3/mole (calc VP/Wsol)
Vapor Press : 0.003 mm Hg (user-entered)
Log Kow : 0.5 (user-entered)
Soil Koc : 1.3 (calc by model)
Mass Amount Half-Life Emissions
(percent) (hr) (kg/hr)
Air 1.73e-007 2.15 0
Water 99.8 900 1000
Soil 0.000496 1.8e+003 0
Sediment 0.198 8.1e+003 0
Fugacity Reaction Advection Reaction Advection
(atm) (kg/hr) (kg/hr) (percent) (percent)
Air 1.41e-018 0.000316 9.8e-006 3.16e-005 9.8e-007
Water 1.11e-014 435 565 43.5 56.5
Soil 1.86e-018 0.00108 0 0.000108 0
Sediment 1.07e-014 0.0957 0.0224 0.00957 0.00224
Persistence Time: 566 hr
Reaction Time: 1.3e+003 hr
Advection Time: 1e+003 hr
Percent Reacted: 43.5
Percent Advected: 56.5
Half-Lives (hr), (based upon Biowin (Ultimate) and Aopwin):
Air: 2.147
Water: 900
Soil: 1800
Sediment: 8100
Biowin estimate: 2.514 (weeks-months)
Advection Times (hr):
Air: 100
Water: 1000
Sediment: 5e+004
______________________________________________________________________________________________________________
Level III Fugacity Model (Full-Output): Emission into air
=======================================
Chem Name : 2-Propenamide, N- 3-(dimethylamino)propyl -2-methyl-
Molecular Wt: 170.26
Henry's LC : 6.72e-010 atm-m3/mole (calc VP/Wsol)
Vapor Press : 0.003 mm Hg (user-entered)
Log Kow : 0.5 (user-entered)
Soil Koc : 1.3 (calc by model)
Mass Amount Half-Life Emissions
(percent) (hr) (kg/hr)
Air 0.0233 2.15 1000
Water 33.2 900 0
Soil 66.7 1.8e+003 0
Sediment 0.0658 8.1e+003 0
Fugacity Reaction Advection Reaction Advection
(atm) (kg/hr) (kg/hr) (percent) (percent)
Air 3.62e-013 81.4 2.52 8.14 0.252
Water 7.11e-015 277 360 27.7 36
Soil 4.79e-013 278 0 27.8 0
Sediment 6.82e-015 0.061 0.0143 0.0061 0.00143
Persistence Time: 1.08e+003 hr
Reaction Time: 1.7e+003 hr
Advection Time: 2.99e+003 hr
Percent Reacted: 63.7
Percent Advected: 36.3
Half-Lives (hr), (based upon Biowin (Ultimate) and Aopwin):
Air: 2.147
Water: 900
Soil: 1800
Sediment: 8100
Biowin estimate: 2.514 (weeks-months)
Advection Times (hr):
Air: 100
Water: 1000
Sediment: 5e+004
Applicant's summary and conclusion
- Conclusions:
- Using a valid Fugacity modeling method (Mackay Level III) the potential environmental distribution of N[3-Dimethylamino)propyl]methacrylamide was calculated. Emissions into water basically stay there while emissions into air are partly removed by photodegradation while other parts partition to the soil and water compartments. It should be noted that the model substantially over-estimates the persistence time in water and soil. In reality the substance is readily biodegradable and the persistence times are lower.
- Executive summary:
According to the model calculation, emissions into water basically stay there while emissions into air are partly removed by photodegradation while other parts partition to the soil and water compartments. It should be noted that the model substantially over-estimates the persistence time in water and soil. In reality the substance is readily biodegradable and the persistence times are lower.
Emission into water:
Mass Amount Half-Life Emissions
(percent) (hr) (kg/hr)
Air 1.73e-007 2.15 0
Water 99.8 900 1000
Soil 0.000496 1.8e+003 0
Sediment 0.198 8.1e+003 0
_______________________________________
Emission into air:
Mass Amount Half-Life Emissions
(percent) (hr) (kg/hr)
Air 0.0233 2.15 1000
Water 33.2 900 0
Soil 66.7 1.8e+003 0
Sediment 0.0658 8.1e+003 0
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