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EC number: 909-082-0 | CAS number: 938065-79-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 16 October 2004 - 17 January 2005
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study according to GLP, but no recovery for the BOC derivatitsation and no spiked samples to assess recovery
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 005
- Report date:
- 2005
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- Reaction mass of 5,12-dihydro-2,9-dimethylquino[2,3-b]acridine-7,14-dione and 5,12-dihydro-2-methylquino[2,3-b]acridine-7,14-dione and 5,12-dihydroquino[2,3-b]acridine-7,14-dione
- EC Number:
- 909-082-0
- Cas Number:
- 938065-79-3
- Molecular formula:
- Unspecified
- IUPAC Name:
- Reaction mass of 5,12-dihydro-2,9-dimethylquino[2,3-b]acridine-7,14-dione and 5,12-dihydro-2-methylquino[2,3-b]acridine-7,14-dione and 5,12-dihydroquino[2,3-b]acridine-7,14-dione
Constituent 1
Study design
- Analytical method:
- high-performance liquid chromatography
- other: UV/VIS spectrometry for n-octanol phase
Results and discussion
Partition coefficientopen allclose all
- Type:
- Pow
- Partition coefficient:
- 248.577
- Temp.:
- 21 °C
- pH:
- 7.15
- Type:
- log Pow
- Partition coefficient:
- > 2.4
- Temp.:
- 21 °C
- pH:
- 7.15
- Details on results:
- The concentration of the test item in the aqueous phase was below the concentration of the smallest calibration point of 0.0063126 mg/L in all six determinations. All values given are means from six determinations (rounded values):
concentration in n-octanol phase: 1.569 mg/L (mean), 1.532 - 1.590 mg/L (range)
Pow: range: 242.689-251.877, standard deviation: 3.864
log Pow: range: >2.39 - >2.40, standard deviation: 0.007
pH: range: 6.97-7.32 (aqueous phase).
Any other information on results incl. tables
The mass balance was calculated for each of the six test vessels to check the analytical work and yielded recoveries of the test item of 92%, 93%, 94% (one vessel each) and 95% (three vessels).
Applicant's summary and conclusion
- Conclusions:
- The partition coefficient (log Pow) of the test item at 21°C was >2.4.
- Executive summary:
The partition coefficient was determined in a guideline study using the flask shaking method with analysis by HPLC and UV/VIS spectrometry. The log Pow was >2.4 at 21°C.
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