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EC number: 272-745-1 | CAS number: 68910-55-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 22 November 2004 to 26 November 2004
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Testing done as per the UK GLP Regulations (1999) and OECD Principles as reported in the study report. Analytical monitoring of the nominal concentrations, however, was not conducted.
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Deviations:
- no
- Principles of method if other than guideline:
- Besides the OECD method, the supporting method cited is the Paris Commission, Protocol for a Fish Acute Toxicity Test, Oslo and Paris Commission (PARCOM, 1995).
- GLP compliance:
- yes
- Remarks:
- Testing done as per the UK GLP Regulations (1999) and OECD Principles
- Analytical monitoring:
- no
- Details on sampling:
- A range-finding test was not conducted. The definitive range was selected based on other, in-house tests.
- Vehicle:
- no
- Details on test solutions:
- Water Accommodated Fractions (WAFs) of the test material were prepared in artificial seawater. The nominal concentrations based on the test material, organolignite, for the definitive test included the following: 100.0, 177.8, 316.2, 562.3 and 1000.0 mg/L.
- Test organisms (species):
- other: Scophthalmus maximus
- Details on test organisms:
- Common and species name: Juvenile turbot (Scophthalmus maximus)
Supplier: France Turbot, L'Epine, France
Batch history: Test organisms received on 10 November 2004 (batch no.: SM04007).
Observations: Batch free of malformations and appearing in good health - Test type:
- semi-static
- Water media type:
- saltwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Test temperature:
- Ranged from 15 degrees C plus or minus 1.5 degrees C
- pH:
- Ranged from 7.71 to 8.41
- Dissolved oxygen:
- Ranged from 91.6% to 100% saturation
- Salinity:
- Ranged from 32.1 parts per thousand (ppt) to 35.2 ppt
- Nominal and measured concentrations:
- WAFs:
100.0, 177.8, 316.2, 562.3 and 1000.0 mg/L - Details on test conditions:
- Testing media: Artificial seawater from Coral Reef, Kent Sea Salt, Red Sea Fish Pharm.
Solubility of test material: sample described as insoluble in seawater
Test duration: 96 hours
Test endpoint: cessation of movement and failure to respond to tactile stimulation
Test parameters: dissolved oxygen (DO), pH, temperature and salinity values recorded at 24 hour intervals - Reference substance (positive control):
- yes
- Remarks:
- 3,5-dichlorophenol - report states that "DCP result for the most recent Turbot batch tested prior to this study was >0.6 mg/L"
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- Lethal concentration 50% (LC50) for 96 hour time period:
>1000 mg/L
Lethal concentration 50% (LC50) for 72 hour time period:
>1000 mg/L
Lethal concentration 50% (LC50) for 48 hour time period:
>1000 mg/L
Lethal concentration 50% (LC50) for 24 hour time period:
>1000 mg/L
NOEC 96h: 1000 mg/L
LOEC 96h: >1000 mg/L
No mortality in any concentrations or the control were observed. - Results with reference substance (positive control):
- The test data for the reference substance, 3,5-dichlorophenol (referred to as DCP in the study report), are not presented. However, the study report does state that the, "DCP result for the most recent Turbot batch tested prior to this study was 0.6 mg/L."
- Sublethal observations / clinical signs:
Validity of the test
-Test Quality Criteria
These quality criteria are in the OECD 203 guideline.
1. Mortality in the control must not exceed 10 % (or one fish if less than ten are used) by the end of the test. 2. The dissolved oxygen concentration must be at least 60 % of initial value. 3. The measured values of pH solution should not change more than 1 pH unit. 4. The test substance concentration in test mixtures should not decrease under 80 % of the initial concentration.Quality criteria at points 1, 2 and 3 were fulfilled. No analytical determination of the test material in the WAFs was noted in the study report. Therefore, #4 test validity quality criterion was not addressed.
- Validity criteria fulfilled:
- yes
- Conclusions:
- The 96h LC50 for the Scophthalmus maximus (juvenile turbot) was calculated as > 1000 mg/L, based on nominal Water Accommodated Fraction concentrations. There was no observed mortality in the control vessels nor or in any of the tested material concentrations (100.0, 177.8, 316.2, 562.3, and 1000.0 mg/L in WAFs) for a 96 hour exposure period. All parameters measured in this study lay within acceptable tolerance limits.
- Executive summary:
The acute toxicity of the test substance, organolignite, to juvenile turbot, Scophthalmus maximus, was determined in accordance with test methods OECD 203 (1992) and PARCOM (1995). Fish were exposed in semi-static conditions for 96 hours to nominal water accommodated fraction (WAF) concentrations of the test substance of 100.0, 177.8, 316.2, 562.3, and 1000.0 mg/L. No mortality was observed in any of the test concentrations or in the control.
Reference
Description of key information
The 96h LC50 for the Scophthalmus maximus (juvenile turbot) was calculated as > 1000 mg/L, based on nominal Water Accommodated Fraction concentrations. There was no observed mortality in the control vessels nor in any of the tested material concentrations (100.0, 177.8, 316.2, 562.3, and 1000.0 mg/L in WAFs) for the 96 hour exposure period. All parameters measured in this study lay within acceptable tolerance limits.
Key value for chemical safety assessment
Marine water fish
Marine water fish
- Effect concentration:
- 1 000 mg/L
Additional information
The acute toxicity of the test substance, organolignite, to juvenile turbot, Scophthalmus maximus, was determined in accordance with test methods OECD 203 (1992) and PARCOM (1995). Fish were exposed in semi-static conditions for 96 hours to nominal water accommodated fraction (WAF) concentrations of the test substance of 100.0, 177.8, 316.2, 562.3, and 1000.0 mg/L. No mortality was observed in any of the test concentrations or in the control. The LC50 for the marine fish species is > 1000 mg/L.
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