Registration Dossier
Registration Dossier
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EC number: 239-888-1 | CAS number: 15790-07-5 This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 15985:1.
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Based on the prediction done using the OECD QSAR toolbox version 3.3 with log kow as the primary descriptor and considering the six closest read across substances, toxicity on Oncorhynchus mykiss (previous name: Salmo gairdneri) was predicted for aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]- 2-naphthalenesulfonic acid complex (15790-07-5). The LC50 value was estimated to be 3.638 mg/l when aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex exposed to Oncorhynchus mykiss (previous name: Salmo gairdneri) for 672hrs.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 3.638 mg/L
Additional information
Based on the various predicted data for the target chemical and experimental data for read across chemicals study have been reviewed to determine the toxic nature of target chemical aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex (15790-07-5) on the growth of fish. The studies are as mentioned below:
In the first key study for the target chemical used based on the prediction done using the OECD QSAR toolbox version 3.3 with log kow as the primary descriptor and considering the six closest read across substances, toxicity on Oncorhynchus mykiss (previous name: Salmo gairdneri) was predicted for aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]- 2-naphthalenesulfonic acid complex (15790-07-5). The LC50 value was estimated to be 3.638 mg/l when aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex exposed to Oncorhynchus mykiss (previous name: Salmo gairdneri) for 672hrs.
Similarly in the second predicted report which was based on the prediction done using ECOSAR version 1.1, the long term toxicity on fish was predicted for test substance aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex (15790-07-5). On the basis of effects observed in a static freshwater system, the NOEC value for the substance is estimated to be 107.088mg/l for fish for 28 days of exposure duration. Based on this value, it can be concluded that the test chemical aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex (15790-07-5) can be considered as non-toxic to fish at environmentally relevant conentrations and can be considered not-classified as per the CLP classification criteria.
Based on the predicted value, it can be concluded that the test chemical aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex (15790-07-5) can be considered as non-toxic to fish at environmentally relevant conentrations and can be considered not-classified as per the CLP classification criteria.
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