Registration Dossier
Registration Dossier
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EC number: 415-750-8 | CAS number: 106447-44-3 7-PACA
Guidance on Safe Use
Administrative data
First-aid measures
Emergency measure - Inhalation: Remove casualty to fresh air. If breathing is difficult give
oxygen. If breathing ceases give artificial respiration.
Seek immediate medical attention.
Emergency measure - Eyes: Flush affected eye with copious amount of water, for at
least 15 minutes. Seek medical attention.
Emergency measure - Skin: Remove contaminated clothing. Wash affected area with
copious amounts of water, for at least 15 minutes. If signs
of irritation occur, seek medical attention.
Emergency measure - Ingestion: Do NOT induce vomiting. Seek immediate medical attention.
Fire-fighting measures
Recommended extinguishing agent: use appropriate medium for the underlying cause of fire
(e.g. water spray, carbon dioxide, dry chemical or foam)
Product arising from burning: Oxides of carbon, nitrogen and sulphur.
Product determined by test: N
Protective equipment: Fire-fighters should wear full (impervious) protective
clothing including self contained breathing apparatus.
Accidental release measures
Emergency measures in case of spillage: Wear full protective clothing: overalls, rubber boots and
gloves, eye protection and self contained respirator when
cleaning up a spill. Collect spilled material to minimize
dust geneartion: use wet mop, damp sponge or wet/dry HEPA
vacuum. Place collected material in suitable container for
disposal. Spill should be washed and well ventilated.
Handling and storage
Handling: Engineering controls in the form of local exhaust
ventilation is provided at the reactor. When engineering
controls are not sufficient to control dust exposure,
approved respirator protection should be worn. For
manufacturing areas skin protection should be provided in
the form of overalls, or full air suits along with
impermeable gloves. Rubber, neoprene or other gloves may be
required if solvents, corrosives or other chemicals are
present. Chemical safety glasses should be worn if a
full-face respirator is not worn.
Storage: Store in sealed unbreakable containers, in a cool, dry place
protected from light.
Ensure conatiners are correctly labelled.
Packaging of the substance and or preparation: Un approved fibre drums.
Transport information
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Marine transport (UN RTDG/IMDG)
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Air transport (UN RTDG/ICAO/IATA)
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Special provisions / remarks
- Remarks:
- Transport: No UN number has been assigned. Use normal procedure for
transport of industrial chemical.
Transport in the above storage conditions. Containers should
be secured against falling.
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Exposure controls / personal protection
Stability and reactivity
Danger other than fire: None known.
Chemical reaction with water: None known.
Dust explosion: This powder as a dust cloud is extremely sensitive to
electrical ignition from static discharges and has a strong
explosion severity. The material has high resistivity and a
long charge time and the potential for it to store
substantial static electrical charge is expected to be high.
Standard bounding and grounding protection of storage,
transfer and process equipment is recommended to control
static charges.
Dust explosion determined by test: N
Disposal considerations
Industry - Possibility of recovery/recycling: 7-PACA is consumed in the drug synthesis reaction in which
it is employed. Significant residual levels in reactor
effluent are not expected. No practical method of
recovery/recycling is known.
Industry - Possibility of neutralisation: No method chemical neutralisation is known.
Industry - Possibility of destruction: controlled discharge: Trace quantities can be destroyed by biological oxidation in
a waste water treatment plant. National regulations must be
observed. Code A641
Industry - Possibility of destruction - incineration: Incineration is recommended for large quantities. A
closed-cycle incineration with scrubbers should be used.
National regulations must be observed. Code: A643
Industry - Possibility of destruction - water purification: Trace quantities of material inn aqueous washes or waste
streams can be treated in a biological treatment plant to
discharge to a municipal treatment plant.
Industry - Possibility of destruction - other: Not recommended.
Public at large - Possibility of recovery/recycling: 7-PACA is not intended for public use.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
