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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
equivalent or similar to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes
Type of method:
flask method
Water solubility:
5 910 mg/L
Conc. based on:
test mat.
Incubation duration:
24 h
Temp.:
20 °C
pH:
2.7
Remarks on result:
other: mean value from 3 single values
Details on results:
In the preliminary test a water solubility of 5460 mg/L was obtained.
Conclusions:
The water solubility of 5910 mg/L (mean value) was measured at 20 °C and pH 2.7.
Executive summary:

The study was performed according to guideline A.6 for determination of water solubility, EG-guideline 92/69 by the shake flask method at 20 °C and pH 2.7. After agitating time of 24 hours the test concentration was determined by HPLC-analysis. A water solubility of 5190 mg/L was measured (mean value from 3 single values). In the preliminary test a water solubility of 5460 mg/L was obtained.

Description of key information

The water solubility of 5910 mg/L was measured at 20 °C and pH 2.7.

Key value for chemical safety assessment

Water solubility:
5 910 mg/L
at the temperature of:
20 °C

Additional information

Result of the preliminary test: 5460 mg/L.

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