Registration Dossier
Registration Dossier
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EC number: 214-244-2 | CAS number: 1117-31-3
Endpoint summary
Administrative data
Description of key information
Additional information
Acute tests evaluating the toxicity of 1,3-butylene diacetate (CAS 1117-31-3) to aquatic organisms from three different trophic levels are available. Fish turned out to be the most sensitive taxonomic group with a LC50 (96 h) of 39 mg/L (nominal), whereas no toxicity was observed in aquatic invertebrates up to a concentration of 100 mg/L after 48 h (nominal). An ErC50 (72 h) > 100 mg/L (> 60 mg/L (geometric mean)) was reported for freshwater algae. Long-term toxicity testing was not deemed necessary. The environmental exposure assessment for1,3-butylene diacetate according to Annex XI, Section 3 according to Regulation (EC) No 1907/2006 indicates no risk for the aquatic compartment (all RCR < 1; please refer to Chapter 9 and 10 of the Chemical Safety Report for detailed information). Thus, long-term testing with aquatic invertebrates and fish is not deemed necessary.
1,3-butylene diacetate did not cause inhibition of biodegradation in a study according to OECD 301B with activated sludge microorganisms. No toxicity/inhibition of degradation was observed at the applied test concentration of 18.1 mg/L in the toxicity control. A NOEC (14 d) of ≥ 18.1 mg/L was derived. The overall potential to cause inhibition of activated sludge microorganisms is low and significant inhibition of the subsequent degradation process in sewage treatment plants is not expected. The environmental exposure assessment for1,3-butylene diacetate according to Annex XI, Section 3 according to Regulation (EC) No 1907/2006 indicates no risk for STP microorganisms (all RCR < 1; please refer to Chapter 9 and 10 of the Chemical Safety Report for detailed information).
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