Registration Dossier

Administrative data

Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2009

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 111 (Hydrolysis as a Function of pH)
Deviations:
no
GLP compliance:
yes (incl. certificate)

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Radiolabelling:
no

Study design

Analytical monitoring:
yes
Duration of testopen allclose all
Duration:
5 d
pH:
9
Temp.:
50
Initial conc. measured:
191 mg/L
Duration:
5 d
pH:
7
Temp.:
50
Initial conc. measured:
191 mg/L
Duration:
5 d
pH:
4
Temp.:
50
Initial conc. measured:
191 mg/L

Results and discussion

Transformation products:
not measured
Total recovery of test substance (in %)open allclose all
% Recovery:
97.69
St. dev.:
0
pH:
4
Temp.:
50 °C
Duration:
5 d
% Recovery:
98.81
St. dev.:
0
pH:
7
Temp.:
50 °C
Duration:
5 d
% Recovery:
99.6
St. dev.:
0
pH:
9
Temp.:
50
Duration:
5 d
Dissipation DT50 of parent compoundopen allclose all
pH:
4
Temp.:
25 °C
DT50:
> 1 yr
Type:
not specified
pH:
7
Temp.:
25
DT50:
> 1 yr
Type:
not specified
pH:
9
Temp.:
25
DT50:
> 1 yr
Type:
not specified

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
At pH 4, 7 and 9 no signs of hydrolysis were oberved. Therefore the test item can be considered as hydrolytically stable ate these pH values.