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EC number: 413-330-9 | CAS number: 134724-55-3 SUMIKARON BRILLIANT RED S-BWF
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro gene mutation study in bacteria
- Remarks:
- Type of genotoxicity: gene mutation
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Part of the SNIF file, which was accepted by the Belgian national authority for NONS
Data source
Referenceopen allclose all
- Reference Type:
- other company data
- Title:
- Unnamed
- Report date:
- 1994
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
- Report date:
- 1994
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 471 (Bacterial Reverse Mutation Assay)
- Version / remarks:
- OECD (Ames-Test)
- GLP compliance:
- not specified
- Type of assay:
- bacterial reverse mutation assay
Test material
- Reference substance name:
- 3-phenyl-7-[4-(tetrahydrofurfuryloxy)phenyl]-1,5-dioxa-s-indacen-2,6-dione
- EC Number:
- 413-330-9
- EC Name:
- 3-phenyl-7-[4-(tetrahydrofurfuryloxy)phenyl]-1,5-dioxa-s-indacen-2,6-dione
- Cas Number:
- 134724-55-3
- Molecular formula:
- Hill formula: C27H20O6 CAS formula: C27H20O6
- IUPAC Name:
- 6-{4-[(oxolan-2-yl)methoxy]phenyl}-12-phenyl-4,10-dioxatricyclo[7.3.0.0³,⁷]dodeca-1(12),2,6,8-tetraene-5,11-dione
- Details on test material:
- No further information was reported/requested within the SNIF file
No further information was reported within the SNIF file, nor was it requested from the Belgian CA
Constituent 1
Method
- Target gene:
- his operon
Species / strain
- Species / strain / cell type:
- S. typhimurium, other: TA 98, 100, 1535, 1537, 1538
- Additional strain / cell type characteristics:
- not specified
- Metabolic activation:
- with and without
- Metabolic activation system:
- liver S9-mix of induced rats
- Test concentrations with justification for top dose:
- with metabolic activation: 0.5 - 500 µg/plate (TA 100)
1.5 - 500 µg/plate (remaining strains)
>= 500 µg/plate precipitation
without metabolic activation: 0.015 - 5 µg/plate (TA 100) )
0.5 - 150 µg/plate (remaining strains)
>= 150 µg/plate precipitation
- Vehicle / solvent:
- Solvent: DMSO
Controls
- Untreated negative controls:
- other: Not reported within the SNIF file
- Negative solvent / vehicle controls:
- other: Not reported within the SNIF file
- True negative controls:
- other: Not reported within the SNIF file
- Positive controls:
- yes
- Positive control substance:
- other: Not reported within the SNIF file
- Details on test system and experimental conditions:
- Not reported within the SNIF file
- Evaluation criteria:
- Not reported within the SNIF file
- Statistics:
- Not reported within the SNIF file
Results and discussion
Test resultsopen allclose all
- Species / strain:
- S. typhimurium, other: TA 98, 100
- Metabolic activation:
- with and without
- Genotoxicity:
- positive
- Cytotoxicity / choice of top concentrations:
- cytotoxicity
- Vehicle controls validity:
- other: Not reported within the SNIF file
- Untreated negative controls validity:
- other: Not reported within the SNIF file
- Positive controls validity:
- valid
- Species / strain:
- S. typhimurium, other: TA 1535, 1537, 1538
- Metabolic activation:
- with
- Genotoxicity:
- negative
- Cytotoxicity / choice of top concentrations:
- cytotoxicity
- Remarks:
- (> 500 µg/plate)
- Vehicle controls validity:
- other: Not reported within the SNIF file
- Untreated negative controls validity:
- other: Not reported within the SNIF file
- Positive controls validity:
- valid
- Species / strain:
- S. typhimurium, other: TA 1535, 1537, 1538
- Metabolic activation:
- without
- Genotoxicity:
- negative
- Cytotoxicity / choice of top concentrations:
- cytotoxicity
- Remarks:
- (> 150 µg/plate)
- Vehicle controls validity:
- other: Not reported within the SNIF file
- Untreated negative controls validity:
- other: Not reported within the SNIF file
- Positive controls validity:
- valid
- Additional information on results:
- Reported in SNIF - Notification number: 05-02-0423; Report date: 1994-01-17= date of registration
- Remarks on result:
- other: strain/cell type: S. typhimurium TA 98, 100
- Remarks:
- Migrated from field 'Test system'.
Any other information on results incl. tables
Part of the SNIF file, which was accepted by the national authority for NONS
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information):
positive
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