Registration Dossier
Registration Dossier
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EC number: 413-330-9 | CAS number: 134724-55-3 SUMIKARON BRILLIANT RED S-BWF
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Part of the SNIF file, which was accepted by the Belgian national authority for NONS
Data source
Referenceopen allclose all
- Reference Type:
- other company data
- Title:
- Unnamed
- Report date:
- 1994
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
- Report date:
- 1994
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method B.1 (Acute Toxicity (Oral))
- GLP compliance:
- not specified
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- 3-phenyl-7-[4-(tetrahydrofurfuryloxy)phenyl]-1,5-dioxa-s-indacen-2,6-dione
- EC Number:
- 413-330-9
- EC Name:
- 3-phenyl-7-[4-(tetrahydrofurfuryloxy)phenyl]-1,5-dioxa-s-indacen-2,6-dione
- Cas Number:
- 134724-55-3
- Molecular formula:
- Hill formula: C27H20O6 CAS formula: C27H20O6
- IUPAC Name:
- 6-{4-[(oxolan-2-yl)methoxy]phenyl}-12-phenyl-4,10-dioxatricyclo[7.3.0.0³,⁷]dodeca-1(12),2,6,8-tetraene-5,11-dione
- Details on test material:
- Not reported within the SNIF file
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Sprague-Dawley
- Sex:
- male/female
- Details on test animals or test system and environmental conditions:
- Not reported within the SNIF file
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- maize oil
- Details on oral exposure:
- Not reported within the SNIF file
- Doses:
- 5000 mg
- No. of animals per sex per dose:
- 5
- Control animals:
- other: Not reported within the SNIF file
- Details on study design:
- Not reported within the SNIF file
- Statistics:
- Not reported within the SNIF file
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 5 000 mg/kg bw
- Mortality:
- Male: 5000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Female: 5000 mg/kg bw; Number of animals: 5; Number of deaths: 0 - Clinical signs:
- other: Signs of toxicity related to dose levels: piloerection evident in all animals immediately after application, recovers within 1 d
- Gross pathology:
- Effects on organs:
no effects - Other findings:
- Not reported within the SNIF file
Any other information on results incl. tables
Part of the SNIF file, which was accepted by the Belgian national authority for NONS
reported in SNIF file-Notification number: 05-02-0423
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
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