Registration Dossier

Administrative data

Endpoint:
respiratory sensitisation: in vivo
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: No test guideline followed, incompletely documented, and no data on purity.

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Experimentelle Untersuchungen der allergenen Wirkung von Ortho- und Paranitrochlorbenzol (deutsche Übersetzung aus dem Russischen)
Author:
Rusakov NV et al.
Year:
1973
Bibliographic source:
Gig. Sanit., Heft 3, 13-16
Reference Type:
other: OECD SIDS
Title:
1-Chloro-2-nitrobenzene, CAS: 88-73-3
Author:
OECD SIDS
Year:
2001
Bibliographic source:
SIDS Initial Assessment Report for SIAM 13

Materials and methods

Principles of method if other than guideline:
The rats were exposed via inhalation to o-chloronitrobenzene for 5 months.
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Test system

Route of induction exposure:
inhalation
Route of challenge exposure:
inhalation
Vehicle:
not specified

Results and discussion

Results:
Sensitising

Applicant's summary and conclusion

Interpretation of results:
sensitising