Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP. Guideline study

Data source

Reference
Reference Type:
other: Body responsible for the test
Title:
Unnamed
Year:
2004
Report date:
2004

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
456-160-0
EC Name:
-
Cas Number:
73942-87-7
Molecular formula:
C12H13NO3
IUPAC Name:
7,8-dimethoxy-2,3-dihydro-1H-3-benzazepin-2-one

Test organisms

Test organisms (species):
other: activated sewage sludge

Study design

Test type:
static
Total exposure duration:
3 h

Results and discussion

Effect concentrationsopen allclose all
Duration:
3 h
Dose descriptor:
EC50
Effect conc.:
> 1 000 mg/L
Duration:
3 h
Dose descriptor:
NOEC
Effect conc.:
>= 1 000 mg/L

Applicant's summary and conclusion

Conclusions:
Under the experimental conditions, the 3-hour EC50 of the test item Veralactame is > 1000 mg/l for activated sludge.
The test item should be considered as non-toxic for the micro-organisms of a water treatment plant.