Registration Dossier
Registration Dossier
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EC number: 619-997-4 | CAS number: 764667-65-4
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro gene mutation study in bacteria
- Remarks:
- Type of genotoxicity: gene mutation
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Safety data sheet of the supplier
- Title:
- Safety data sheet of the Ketoamide
- Author:
- Merck
- Year:
- 2 009
- Bibliographic source:
- Safety data sheet of the supplier
- Report date:
- 2009
Materials and methods
- Principles of method if other than guideline:
- Not available
- GLP compliance:
- not specified
- Type of assay:
- bacterial reverse mutation assay
Test material
- Reference substance name:
- 1-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butane-1,3-dione
- Cas Number:
- 764667-65-4
- Molecular formula:
- C16H12F6N4O2
- IUPAC Name:
- 1-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butane-1,3-dione
Constituent 1
Results and discussion
Test results
- Species / strain:
- not specified
- Metabolic activation:
- not specified
- Genotoxicity:
- negative
- Cytotoxicity / choice of top concentrations:
- not specified
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information):
negative
Not mutagenic in Ames test.
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