Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
developmental toxicity
Type of information:
experimental study planned
Study period:
Should be available approximately 6 months after dosing commences. Planned Studies on DIPE (CAS 108-20-3) should be completed before commencing tests since a positive result in that study will result in a positive result for OC4 Strom4.

Data source

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 414 (Prenatal Developmental Toxicity Study)
Version / remarks:
; exposure route: oral or inhalative
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-(butan-2-yloxy)butane; 2-(propan-2-yloxy)propane; 2-methylpropan-2-ol; butan-2-ol
EC Number:
903-919-3
Molecular formula:
Not applicable as multiconstituent substance.
IUPAC Name:
2-(butan-2-yloxy)butane; 2-(propan-2-yloxy)propane; 2-methylpropan-2-ol; butan-2-ol

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Results (fetuses)

Fetal abnormalities

Abnormalities:
not specified

Overall developmental toxicity

Developmental effects observed:
not specified

Applicant's summary and conclusion