Registration Dossier
Registration Dossier
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EC number: 203-197-3 | CAS number: 104-38-1
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Based on negligible emission to a sewage treatment plant and the factors indicating microbial toxicity is unlikely to occur, the endpoint is waived and no testing is proposed.
Key value for chemical safety assessment
Additional information
There are no reliable toxicity data for microoganisms with HQEE.Under Column 2 of the Annex VIII of Regulation (EC) No 1907/2006, studies of the effects on activated sludge microorganisms need not be conducted if there is no emission to a sewage treatment plant or if there are mitigating factors indicating that microbial toxicity is unlikely to occur. It is proposed that testing is waived as exposure potential is negligible as the substance is an intermediate product. The test substance is a monomer where the solid product is blended with non-aqueous substances. Once polymerised the substance is chemically bound into the polymer matrix of the article therefore there is no downstream exposure. There is negligible exposure to aqueous process streams during downstream use and hence also negligible emission to a sewage treatment plant. Therefore, microbial exposure is negligible. Additionally, studies on toxicity to aquatic organisms indicate that microbial toxicity is unlikely to occur. Both long and short-term toxicity to the most sensitive aquatic organism tested was >100 mg/L. Therefore, based on negligible emission to a sewage treatment plant and the factors indicating microbial toxicity is unlikely to occur, the endpoint is waived and no testing is proposed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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