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EC number: 259-515-6
CAS number: 55184-72-0
dermal dose, male albino rabbits, LD50> 5mL/kg
Onset of (S) Signs, (D) Death, Hours and Days
Time of (R)Recovery, Days
LD50 Greater than 5 mL/kg
Signs of Intoxication:
Diarrhea in 2 animals.
Skin irritation: Mild to
moderate erythema. Product formed waxy film where applied.
Gross autopsy: Normal.
2 Groups of 5 male albino rabbits underwent a
covered application in continuous 24-hour contact with the shaved
skin with the test item Butanedioic acid, sulfo-, 1,4 -ditridecyl ester,
sodium salt (70% active ingredient) at dosages of 5.0 mL/kg and 2.5
mL/kg, corresponding to 3500 and 1750 mg active ingredient/kg bw. There
were no mortalities. There were 2 animals with diarrhea but gross
autopsy was normal. The oral LD50 of the test item was > 5 mL/kg bw or >
3500 mg active ingredient/kg bw. This test item is
considered to be practically non-toxic by single skin applications.
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