Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Water solubility

Currently viewing:

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2004
Report date:
2004

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
454-140-6
EC Name:
-
Cas Number:
376608-71-8
Molecular formula:
C9H9F2N*C8H8O3
IUPAC Name:
(1R)-2-(3,4-difluorophenyl)cyclopropan-1-aminium (2R)-2-hydroxy-2-phenylacetate
Constituent 2
Reference substance name:
trans-(1R,2S)-2-(3,4-difluorophenyl-cyclopropanaminium (2R)- 2-hydroxy-2-phenylethanoate
IUPAC Name:
trans-(1R,2S)-2-(3,4-difluorophenyl-cyclopropanaminium (2R)- 2-hydroxy-2-phenylethanoate

Results and discussion

Water solubility
Water solubility:
> 6 850 - < 7 150 mg/L
Temp.:
25 °C
pH:
> 5.71 - < 5.78
Details on results:
Result by UV Analysis : 7000 ± 150mg/l at 25°C ± 1°C. Test 1 : 6995mg/l at 25°C ± 1°C. Test 2 : 6983mg/l at 25°C ± 1°C. Test 3 : 6958mg/l at 25°C ± 1°C. Test 4 : 6880mg/l at 25°C ± 1°C. Test 5 : 7095mg/l at 25°C ± 1°C.

Applicant's summary and conclusion