Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
0.003 mg/L
Assessment factor:
1 000
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
0.026 mg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0 mg/L
Assessment factor:
10 000
Extrapolation method:
assessment factor

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
6 mg/L
Assessment factor:
100
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
0.545 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
0.054 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
0.107 mg/kg soil dw
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential to cause toxic effects if accumulated (in higher organisms) via the food chain

Additional information

The PNECfreshwater was derived from most sensitive aquatic toxicity tests for the aquatic compartment, which was the short-term toxicity to Daphnia test. An assessment factor of 1000 was applied (CSA Guidance Document, Chapter R. 10, May 2008), resulting in a PNEC freshwater of 0.00261 mg/L.

The PNEC sediment, PNEC sediment marine and the PNEC soil have been derived using the equilibrium partitioning method using the KOC and the Henry’s law constant of the test substance and the PNEC freshwater or PNEC marine water. Further calculation factors, like the conversion factor from wet to dry, were chosen according to the guidance document R. 10 (May 2008) and R.16 (Feb. 2016).

PNEC sediment

Ksusp-water= 52.167; RHOsusp= 1150

 

PNECfreshwater sed.= (Ksusp-water/RHOsusp)*PNECwater* 1000

                            = (52.167/1150)*0.00261 * 1000

                            = 0.118 mg/kg wwt

                           = 0.545 mg/kg dw

 

PNECmarine sediment= (Ksusp-water/RHOsusp)*PNECmarine water* 1000

                             = (52.167/1150)*0.000261 * 1000

             = 0.0118mg/kg wwt

                            = 0.0545 mg/kg dw

 

PNEC soil:

The PNECsoilwas derived by the equilibrium partitioning method according to guidance document R.10 (May 2008):

Ksoil-water= 61,75; RHOsusp= 1700

 PNECsoil= (Ksoil-water/RHOsusp)*PNECwater*1000 

= (61,75/1700)*0.00261* 1000

 = 0.0948 mg/kg wwt

 = 0.107 mg/kg dw

Conclusion on classification

Invertebrates are the most sensitive species to the toxic effects of 1,6 -dichlorohexane with an acute EC50 of 2.61 mg/L. Furthermore, 1,6 -dichlorohexane was not readily biodegradable. Based on the results obtained, 1,6 -dichlorohexane should be classified as Chronic Category 2, H411 (Toxic to aquatic life with long lasting effects) according to Regulation (EC) No 1272/2008 (CLP/GHS).

According to UN-GHS, the substance is additionally classified and labelled as Aquatic Acute Cat 2 (H401: Toxic to aquatic life.).