2,2,2-trichloro-1-phenylethyl acetate

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

Data is from experimental study report

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

GLP compliance:

no

Type of method:

flask method

Specific details on test material used for the study:

- Name of test material (as cited in study report): 2,2,2-trichloro-1-phenylethyl acetate
- Molecular formula: C10-H9-Cl3-O2
- Molecular weight: 267.538g/mol
- Smiles notation: c1([C@@H](OC(C)=O)C(Cl)(Cl)Cl)ccccc1
- InChl: 1S/C10H9Cl3O2/c1-7(14)15-9(10(11,12)13)8-5-3-2-4-6-8/h2-6,9H,1H3
- Substance type: Organic
- Physical state: solid

Key result

Water solubility:

16.56 mg/L

Conc. based on:

test mat.

Temp.:

25 °C

Remarks on result:

other: slightly soluble

Sample stirring	Concentration obtained on the basis of standard curve	Dilution factor	Solubility value obtained (mg/L)
24 hour	-	-	-
48 hour	12.8501	-	12.8501
72 hour	20.2704	-	20.2704

Considering the water solubility for 48 hrs and 72 hrs the mean water solubility was calculated as follows: Mean water solubility value for 48 hour run sample + 72 hour run sample =(12.8501+20.2704)/2 =16.5602 mg/L

Conclusions:

The water solubilitydetermination of test chemical was done by spectrophotometric method. The water solubility was determined to be 16.5602 mg/L at 25°C.

Executive summary:

The water solubility determination of test chemical was done as per the OECD guideline 105 byspectrophotometric analytical method as per OECD 101. The solubility of test chemical in water was found to be 16.5602 mg/L at 25°C.The above value indicates that substance is slightly soluble in water.

Description of key information

The water solubility determination of test chemical was done as per the OECD guideline 105 byspectrophotometric analytical method as per OECD 101. The solubility of test chemical in water was found to be 16.5602 mg/L at 25°C.The above value indicates that substance is slightly soluble in water.

Key value for chemical safety assessment

Water solubility:

16.56 mg/L

at the temperature of:

25 °C

Additional information

The water solubility determination of test chemical was done as per the OECD guideline 105 byspectrophotometric analytical method as per OECD 101. The solubility of test chemical in water was found to be 16.5602 mg/L at 25°C.The above value indicates that substance is slightly soluble in water.

From other experimental report, water solubility of the test chemical was determined to be 85.5 mg/l at 30°C by Shake flask method.