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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
in vitro gene mutation study in bacteria
Remarks:
Type of genotoxicity: gene mutation
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Title:
No information
Author:
Benigni, R
Year:
2013
Bibliographic source:
OECD Toolbox v3.1 (CCRIS data from 2011)

Materials and methods

Test guideline
Guideline:
OECD Guideline 471 (Bacterial Reverse Mutation Assay)
Version / remarks:
Ames test
GLP compliance:
not specified
Type of assay:
bacterial reverse mutation assay

Test material

Constituent 1
Chemical structure
Reference substance name:
(±)-2-(6-methoxy-2-naphthyl)propionic acid
EC Number:
247-485-7
EC Name:
(±)-2-(6-methoxy-2-naphthyl)propionic acid
Cas Number:
26159-31-9
Molecular formula:
C14H14O3
IUPAC Name:
2-(6-methoxynaphthalen-2-yl)propanoic acid

Method

Species / strain
Species / strain / cell type:
S. typhimurium, other: TA 97A/98/100/102/1537/1538
Metabolic activation:
with and without
Metabolic activation system:
S9

Results and discussion

Test results
Species / strain:
S. typhimurium, other: TA 97A/98/100/102/1537/1538
Metabolic activation:
with and without
Genotoxicity:
negative
Cytotoxicity / choice of top concentrations:
not determined

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information):
negative