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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Link to relevant study record(s)

Description of key information

A 48-hour acute toxicity study was available for Daphnia magna exposed to Diisobutyl Carbinol (DIBC), following standard guidelines.  The resulting 48-hr EC50 value was 47.8 mg/L.

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
47.8 mg/L

Additional information

A 48 -hour acute toxicity study was available for the evaluation of diisobutyl carbinol (DIBC) to the daphnid, Daphnia magna. The study followed GLP, along with standard guidelines and was rated a Klimisch score of 2. The 24 -hour EC50 value ws 86.2 mg/L with a 95% confidence interval of 76.1 to 97.6 mg/L, while the 48 -hour EC50 value was 47.8 mg/L with a 95% confidence interval of 40.1 to 57.1 mg/L. Based on biological interpretation of the data and the highest exposure level exhibiting no immobility, mortality, or sublethal effects, the 48 -hour NOEC was 17.5 mg/L.