Registration Dossier
Registration Dossier
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EC number: 939-420-2 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
A 48-hour acute toxicity study was available for Daphnia magna exposed to Diisobutyl Carbinol (DIBC), following standard guidelines. The resulting 48-hr EC50 value was 47.8 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- LC50
- Effect concentration:
- 47.8 mg/L
Additional information
A 48 -hour acute toxicity study was available for the evaluation of diisobutyl carbinol (DIBC) to the daphnid, Daphnia magna. The study followed GLP, along with standard guidelines and was rated a Klimisch score of 2. The 24 -hour EC50 value ws 86.2 mg/L with a 95% confidence interval of 76.1 to 97.6 mg/L, while the 48 -hour EC50 value was 47.8 mg/L with a 95% confidence interval of 40.1 to 57.1 mg/L. Based on biological interpretation of the data and the highest exposure level exhibiting no immobility, mortality, or sublethal effects, the 48 -hour NOEC was 17.5 mg/L.
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