Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 230-565-0 | CAS number: 7195-44-0
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Toxicity of bis(2,3-epoxypropyl) terephthalate to Activated Sludge in a Respiration Inhibition Test
Key value for chemical safety assessment
- EC50 for microorganisms:
- 2 536.5 mg/L
- EC10 or NOEC for microorganisms:
- 18.6 mg/L
Additional information
In comparison to the inoculum controls the respiration rate of the activated sludge was slightly inhibited by 11.9% at the lowest nominal test concentration of 10 mg/L. At the next higher concentrations of nominal 32 and 100 mg/L the inhibition was 14.3%. The respiration rate of the activated sludge was moderately inhibited by 28.6% at 320 mg/L. At a nominal concentration of 1000 mg/L, the respiration rate was inhibited by 42.9% at a plateau. Concentrations exceeding 1000 mg/L nominal were not tested.
Based on measured inhibition rates, the 3-hour EC10, EC20and EC50and their 95% confidence limits were determined.
The results are listed below:
Parameter EC10 EC20 EC50
Value [mg/L] 18.6 100.5 2536.5
lower 95%-cl 0.1 11.7 817.1
upper 95%-cl 64.0 238.1 180059.8
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
