Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 233-658-4 | CAS number: 10294-34-5
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: A degradation category approach is applied, based on the very rapid hydrolysis of boron trichloride. The description and justification of the category is presented in Section 13.
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
Data source
Reference
- Reference Type:
- other: REACH registration dossier
- Title:
- Unnamed
- Year:
- 2 010
Materials and methods
Test material
- Reference substance name:
- Hydrogen chloride
- EC Number:
- 231-595-7
- EC Name:
- Hydrogen chloride
- Cas Number:
- 7647-01-0
- IUPAC Name:
- chloride
- Reference substance name:
- boric acid
- IUPAC Name:
- boric acid
Constituent 1
Constituent 2
Results and discussion
Any other information on results incl. tables
Hydrochloric acid does not posses any skin sensitizing potential, both at MEST and GPMT.
For boric acid, an experimental study according to OECD 406 and experience with occupationally exposed workers are available. No evidence of skin sensitisation was obtained.
Applicant's summary and conclusion
- Interpretation of results:
- not sensitising
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Boron trichloride is not a skin sensitiser.
- Executive summary:
Boron trichloride is not a skin sensitiser, which is derived from the degradation category approach applied, by transcribing the results of hydrochloric acid and boric acid to boron trichloride.
The description and justification of the category approach is presented in Section 13.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
