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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2014
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: well performed OECD study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2014
Report date:
2014

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
GLP compliance:
no
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
8-[bis(2-hydroxyethyl)amino]-12-[(3-methylphenyl)amino]-10-phenyl-5,10λ⁵-diazatetraphen-10-ylium chloride
EC Number:
941-946-2
Molecular formula:
C33H31ClN4O2
IUPAC Name:
8-[bis(2-hydroxyethyl)amino]-12-[(3-methylphenyl)amino]-10-phenyl-5,10λ⁵-diazatetraphen-10-ylium chloride

Study design

Analytical method:
photometric method

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
-0.16
Temp.:
23 °C
pH:
ca. 2.4
Details on results:
Results in detail:

determ. no. stock solution n-octanol test substance test substance
conc. in n-octanol conc. in water
[ml] [ml] phase [mg/l] phase [mg/l] Log Pow
A1 5 10 119,6 157,4 - 0,12
A2 5 10 122,8 157,1 - 0,11
B1 10 10 155,8 229,2 -0,17
B2 10 10 152,7 219,7 -0,16
C1 20 10 181,5 293,0 -0,21
C2 20 10 188,5 291,0 -0,19
mean -0.16

Any other information on results incl. tables

Recovery rate: 96 - 104 %

pH of aqueous solution : 5.9 - 7.2

Applicant's summary and conclusion

Conclusions:
The Log Pow of the substance is -01,6 at 23°C.
Executive summary:

The Partition Coefficient n-octanol/water of the substance was determined according to OECD guideline 107 with shake flask method and was found to be -0,16 at 23°C