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EC number: 252-043-1 | CAS number: 34454-97-2
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
In a ready biodegradation test under guideline OECD 301B, 0% and 2% CO2 evolution were observed. In an inherent test of biodegradation, the test substance underwent primary transformation (92 % within 14 days and 96.5% within 28 days). Most of the transformation was to a carboxylic acid by dehydration of the alcohol moiety, with no further degradation. C4 sulfonamido alcohol undergoes primary, inherent biodegradation.
Key value for chemical safety assessment
- Biodegradation in water:
- inherently biodegradable, not fulfilling specific criteria
Additional information
Biodegradation of C4 sulfonamido alcohol was examined in a test of ready biodegradability and a test of inherent biodegradability. The ready test was conducted under OECD guideline 301B. Evolved CO2/Theoretical values were zero and two percent in duplicate flasks. A toxicity control using sodium acetate showed little or no inhibition of biodegradation by C4 sulfonamido alcohol. The inherent biodegradability test was conducted using aspects of the Zahn-Wellens and Modified SCAS methods (USEPA OPPTS835.3200 and OPPTS835.3210). Analysis was solely by HPLC-MS. C4 sulfonamido alcohol was mostly removed by day 28 (92 % by day 14, 96.5% by 28 days). A mass balance demonstrated that a carboxylic acid formed by dehydrogenation of the C4 sulfonamido alcohol's hydroxyl group was the most important metabolite (ca. 97% of total). C4 sulfonamido alcohol did not inhibit primary degradation of sodium lauryl sulfate when co-incubated. Dehydration of the terminal hydroxyl group does not lead to CO2 evolution. It is possible that the carboxylic acid formed in the inherent biodegradation study as the major product was also formed in the ready biodegradation study.
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