Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 906-265-7 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 measured values: >100mg/l (48hr), >10000mg/l (24hr) respectively for MEG and DEG. EC50 Value cited in QSAR tool from validation database of 50000mg/l for MEG
QSAR LC50 (48hr) values: 16, 47, 12g/l respectively for MEG, DEG and NaAc.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 10 000 mg/L
Additional information
Measured data is available for two of the three constituents, but not in ideal form to establish an unequivocal value for the EC50. One study is only a limit study for classification purposes and another is only a 24 hour study. QSAR data suggests a very low level of toxicity and that the toxicity decreases with increasing molecular weight of the series. The QSAR does not include a specific class covering acetate salts but predicts that the same neutral organics class can be used as an alternative. The QSAR predicts that sodium acetate will of similar toxicity to MEG (although this is probably an overestimate of toxicity.) From the data available, it seems reasonable and sufficiently conservative to establish a key parameter of 10000mg/l for the EC50 in daphnia.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
