Registration Dossier
Registration Dossier
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EC number: 413-890-4 | CAS number: 82469-79-2
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 982
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- other: Federal Hazardous Substances Act CFR 16.1500.41 as described in National Academy of Science Publications, #1138.
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
- GLP compliance:
- yes
Test material
- Reference substance name:
- -
- EC Number:
- 413-890-4
- EC Name:
- -
- Cas Number:
- 82469-79-2
- Molecular formula:
- C28H50O8
- IUPAC Name:
- 1,2,3-trihexyl 2-(butanoyloxy)propane-1,2,3-tricarboxylate
Constituent 1
Test animals
- Species:
- other: albino rabbit
Test system
- Type of coverage:
- occlusive
- Vehicle:
- other: none. Undiluted agent used.
- Amount / concentration applied:
- 5 mg
- Duration of treatment / exposure:
- 24 h
- Number of animals:
- 6
Results and discussion
In vivo
Resultsopen allclose all
- Irritation parameter:
- erythema score
- Basis:
- mean
- Score:
- 0.4
- Max. score:
- 1
- Remarks on result:
- other: Max. duration: 48 d; Max. value at end of observation period: 0
- Irritation parameter:
- edema score
- Basis:
- mean
- Score:
- 0
- Max. score:
- 0
- Remarks on result:
- other: Max. duration: 0 d; Max. value at end of observation period: 0
- Other effects:
- At 168 hours after dosing a slight desquamation of the
epidermis was seen at the abraided site of one rabbit.
Applicant's summary and conclusion
- Interpretation of results:
- other: not classified
- Conclusions:
- Citroflex B-6 is not a primary skin irritant.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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