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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2005-10-28 to 2006-03-06
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
1995
GLP compliance:
yes
Type of method:
effusion method: vapour pressure balance
Temp.:
20 °C
Vapour pressure:
0 Pa
Key result
Temp.:
25 °C
Vapour pressure:
0 Pa
Temp.:
50 °C
Vapour pressure:
0.001 Pa

The vapour pressure was measured in the temperature range of 24 °C to 117 °C. The measured vapour pressures at the corresponding temperatures are listed in the following table:

Temperature / °C

Vapour pressure / hPa

49.3

8.2x10-6

54.2

1.7x10-5

58.0

2.1x10-5

61.3

2.5x10-5

64.5

3.8x10-5

67.6

4.6x10-5

72.5

9.6x10-5

77.1

1.7x10-4

83.6

4.1x10-4

88.0

7.0x10-4

93.3

1.2x10-3

99.6

2.4x10-3

105.2

3.8x10-3

112.2

8.3x10-3

116.9

1.3x10- 2

 

The values for 20, 25 and 50 °C were calculated, using the Antoine constants A, B and C.

Antoine parameters and extrapolated vapour pressures:

T/°C

log (p/hPa) = A + B/(C + T[°C])

p/hPa

p/Pa

20

A = 13.67309

8.11E-08

8.1E-06

25

B = -6087.03

1.81E-07

1.8E-05

50

C = 273.15

6.86E-06

6.9E-04

Conclusions:
The vapour pressure of the test substance was determined to be 8.1E-06 Pa at 20 °C, 1.8E-05 Pa at 25 °C and 6.9E-04 Pa at 50 °C, respectively.
Executive summary:

A study was conducted according to OECD TG 104 and Regulation (EC) No 440/2008 method A.4 to determine the vapour pressure of the test item. The vapour pressure was measured in the temperature range of 24 °C to 117 °C using the effusion method. The vapour pressure was calculated using the linear regression equation of the Log P versus 1/T function. The vapour pressure of the test substance was determined to be 8.1E-06 Pa at 20 °C, 1.8E-05 Pa at 25 °C and 6.9E-04 Pa at 50 °C, respectively.

Description of key information

The vapour pressure of the test substance was determined to be 8.1E-06 Pa at 20 °C, 1.8E-05 Pa at 25 °C and 6.9E-04 Pa at 50 °C, respectively.

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
25 °C

Additional information

A study was conducted according to OECD TG 104 and Regulation (EC) No 440/2008 method A.4 to determine the vapour pressure of the test item. The vapour pressure was measured in the temperature range of 24 °C to 117 °C using the effusion method. The vapour pressure was calculated using the linear regression equation of the Log P versus 1/T function. The vapour pressure of the test substance was determined to be 8.1E-06 Pa at 20 °C, 1.8E-05 Pa at 25 °C and 6.9E-04 Pa at 50 °C, respectively (reference 4.6-1).